Endocrine and molecular investigations in a cohort of 25 adolescent males with prominent/persistent pubertal gynecomastia

Author:

Paris F.12,Gaspari L.13,Mbou F.4,Philibert P.2,Audran F.2,Morel Y.5,Biason-Lauber A.6,Sultan C.12

Affiliation:

1. Unité d'Endocrinologie-Gynécologie Pédiatriques; Département de Pédiatrie; Hôpital Arnaud-de-Villeneuve; CHU Montpellier et Université Montpellier 1 Montpellier France

2. Département d'Hormonologie (Développement et Reproduction); Hôpital Lapeyronie; CHU Montpellier et Université Montpellier 1 Montpellier France

3. Département de Pédiatrie; Hôpital Caremeau; CHU Nîmes; Nîmes France

4. Département de Pédiatrie; CHU de Fort de France; Martinique

5. Centre de Biologie et Pathologie Est; Bron France

6. Department of Medicine; University of Fribourg; Fribourg Switzerland

Publisher

Wiley

Subject

Urology,Endocrinology,Reproductive Medicine,Endocrinology, Diabetes and Metabolism

Reference45 articles.

1. Gynecomastia: review;Abaci;Pediatr Endocrinol Rev,2007

2. Further evidence of the clinical, hormonal, and genetic heterogeneity of Klinefelter syndrome: a study of 216 infertile Egyptian patients;Abdel-Razic;J Androl,2012

3. Compound heterozygous mutations (Arg 239-stop, Pro 342-Thr) in the CYP17 (P45017 alpha) gene lead to ambiguous external genitalia in a male patient with partial combined 17 alpha-hydroxylase/17,20-lyase deficiency;Ahlgren;J Clin Endocrinol Metab,1992

4. Gynecomastia in puberty is usually asymptomatic and regresses spontaneously;Atabek;J Pediatr Endocrinol Metab,2013

5. A single amino acid substitution in the putative redox partner-binding site of P450c17 as cause of isolated 17,20-lyase deficiency;Biason-Lauber;J Clin Endocrinol Metab,1997

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