Implementation strategies to support ultrasound thyroid nodule risk stratification: A systematic review

Author:

Edwards Matthew1,Brito Juan P.23,Salloum Ramzi G.4,Hoang Jenny5,Singh Ospina Naykky6ORCID

Affiliation:

1. Case Western Reserve University School of Medicine Cleveland Ohio USA

2. Division of Endocrinology, Knowledge and Evaluation Research Unit in Endocrinology (KER_Endo) Mayo Clinic Rochester Minnesota USA

3. Division of Endocrinology Mayo Clinic Rochester Minnesota USA

4. Department of Health Outcomes and Biomedical Informatics University of Florida Gainesville Florida USA

5. Department of Radiology and Radiological Science Johns Hopkins University School of Medicine Baltimore Maryland

6. Division of Endocrinology, Department of Medicine University of Florida Gainesville Florida USA

Abstract

AbstractBackgroundUltrasound risk stratification can improve the care of patients with thyroid nodules by providing a structured and systematic approach for the evaluation of thyroid nodule features and thyroid cancer risk. The optimal strategies to support implementation of high quality thyroid nodule risk stratification are unknown. This study seeks to summarise strategies used to support implementation of thyroid nodule ultrasound risk stratification in practice and their effects on implementation and service outcomes.MethodsThis is a systematic review of studies evaluating implementation strategies published between January 2000 and June 2022 that were identified on Ovid MEDLINE, Ovid EMBASE, Ovid Cochrane, Scopus, or Web of Science. Screening of eligible studies, data collection and assessment for risk of bias was completed independently and in duplicate. Implementation strategies and their effects on implementation and service outcomes were evaluated and summarised.ResultsWe identified 2666 potentially eligible studies of which 8 were included. Most implementation strategies were directed towards radiologists. Common strategies to support the implementation of thyroid nodule risk stratification included: tools to standardise thyroid ultrasound reports, education on thyroid nodule risk stratification and use of templates/forms for reporting, and reminders at the point of care. System based strategies, local consensus or audit were less commonly described. Overall, the use of these strategies supported the implementation process of thyroid nodule risk stratification with variable effects on service outcomes.ConclusionsImplementation of thyroid nodule risk stratification can be supported by development of standardised reporting templates, education of users on risk stratification and reminders of use at the point of care. Additional studies evaluating the value of implementation strategies in different contexts are urgently needed.

Funder

National Cancer Institute

Publisher

Wiley

Subject

Endocrinology, Diabetes and Metabolism,Endocrinology

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