Effects of adalimumab therapy in adult subjects with moderate-to-severe psoriasis on Th17 pathway
Author:
Affiliation:
1. Department of Dermatology; University of Naples Federico II; Naples Italy
Funder
AbbVie
Publisher
Wiley
Subject
Infectious Diseases,Dermatology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jdv.12240/fullpdf
Reference25 articles.
1. Pathogenesis and therapy of psoriasis;Lowes;Nature,2007
2. New concepts in the pathogenesis and treatment of psoriasis: key roles for IL-23, IL-17A and TGF- β1;Blauvelt;Expert Rev Dermatol,2007
3. Further checkpoints in Th1 development;Robinson;Immunity,2002
4. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat;Manel;Nat Immunol,2008
5. IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human;Vanden;Eur J Immunol,2005
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