Characterization of patients with psoriatic arthritis in dermatologic and rheumatologic care: analysis of two registries

Author:

Augustin Matthias1ORCID,Lindner Lisa2ORCID,Kühl Laura1,Weiss Anja2ORCID,Rustenbach Stephan Jeff1,Stephan Brigitte1ORCID,Feuchtenberger Martin3,Mrowietz Ulrich4,Thaçi Diamant5,Staubach Petra6,Baraliakos Xenofon7ORCID,Strangfeld Anja28ORCID,von Kiedrowski Ralph9,Behrens Frank10ORCID,Regierer Anne Constanze2ORCID

Affiliation:

1. Institute for Health Services Research in Dermatology and Nursing (IVDP) University Medical Center Hamburg‐Eppendorf (UKE) Hamburg Germany

2. German Rheumatism Research Center Epidemiology Unit Berlin Germany

3. Department of Internal Medicine II InnKlinikum Burghausen Germany

4. Psoriasis Center Department of Dermatology Venereology and Allergy University Medical Center Schleswig‐Holstein Kiel Campus Kiel Germany

5. Excellence Center for Inflammation Medicine University Medical Center Schleswig‐Holstein Lübeck Campus Lübeck Germany

6. Department of Dermatology University Medical Center Mainz Mainz Germany

7. Rheumazentrum Ruhrgebiet Herne Ruhr University Bochum Bochum Germany

8. Medical Clinic with focus on rheumatology and clinical immunology Charité – Universitätsmedizin Berlin Berlin Germany

9. Dermatology practice Selters Selters Germany

10. Rheumatology University Hospital Fraunhofer Institute for Translational Medicine & Pharmacology ITMP Goethe University and Fraunhofer Cluster of Excellence Immune‐Mediated Diseases CIMD Frankfurt am Main Germany

Abstract

SummaryBackground and objectivePsoriatic arthritis (PsA) is a chronic systemic inflammatory disease affecting the musculoskeletal system, skin and nails. The aim is to characterize sociodemographic and clinical patient profiles documented in dermatologic and rheumatologic care.Patients and MethodsData of 704 patients with PsA from the dermatological Psoriasis Registry PsoBest (PB) and 1066 patients from the rheumatological disease registry RABBIT‐SpA (RS) were analyzed. Comparable anamnestic and clinical variables were identified and descriptively analyzed.ResultsThe mean age was 51.7 years in PB and 51.9 in RS. Disease duration of psoriasis was longer, mean cutaneous severity was higher in PB. However, more patients in RS vs. PB had tender joints and swollen joints. Mean Dermatology Life Quality Index was higher in PB and mean Health Assessment Questionnaire in RS. Patient reported global disease activity and pain were lower in PB. IL‐23 inhibitors were used more frequently in PB, and TNF inhibitors in RS.ConclusionsClinical specialization was associated with different clinical and treatment patterns of PsA. This may indicate a selection by dominant manifestation of psoriatic disease and potentially by effects of health care access. Psoriatic arthritis should be treated in a multidisciplinary approach considering all facets of this complex disease.

Publisher

Wiley

Subject

Dermatology

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