TheJAK2 blockerTG101209 is a potent inhibitor of clonogenic progenitor cell growth in patients with chronic myeloid leukaemia-Reference-Cited by-同舟云学术

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TheJAK2 blockerTG101209 is a potent inhibitor of clonogenic progenitor cell growth in patients with chronic myeloid leukaemia

Published:2017-02-21 Issue:1 Volume:181 Page:137-139
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Demyanets Svitlana¹,Jaeger Eva¹,Pablik Eleonore²,Greiner Georg¹,Herndlhofer Susanne³,Valent Peter³⁴,Schwarzinger Ilse¹

Affiliation:

1. Department of Laboratory Medicine Medical University of Vienna Vienna Austria

2. Centre for Medical Statistics, Informatics and Intelligent Systems Medical University of Vienna Vienna Austria

3. Department of Internal Medicine I, Division of Haematology and Haemostaseology Medical University of ViennaVienna Austria

4. Ludwig Boltzmann Cluster Oncology Medical University of Vienna Vienna Austria

Funder

Austrian Science Fund

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.14508

Reference10 articles.

1. Targeting Primitive Chronic Myeloid Leukemia Cells by Effective Inhibition of a New AHI-1–BCR-ABL–JAK2 Complex

2. JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo

3. BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia

4. Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors

5. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

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3. A facile and high-sensitive bio-sensing of the V617F mutation in JAK2 gene by GSH-CdTe-QDs FRET-based sensor;Heliyon;2022-12

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