AQW051, a novel, potent and selective α7 nicotinic ACh receptor partial agonist: pharmacological characterization and phase I evaluation

Author:

Feuerbach Dominik1,Pezous Nicole1,Weiss Markus1,Shakeri-Nejad Kasra1,Lingenhoehl Kurt1,Hoyer Daniel2,Hurth Konstanze1,Bilbe Graeme3,Pryce Christopher R4,McAllister Kevin1,Chaperon Frederique5,Kucher Klaus5,Johns Donald5,Blaettler Thomas6,Lopez Lopez Cristina5

Affiliation:

1. Novartis Institutes for BioMedical Research; Basel Switzerland

2. Department of Pharmacology and Therapeutics; University of Melbourne; Victoria Australia

3. DNDi - Drugs for Neglected Diseases initiative; Geneva Switzerland

4. Department of Psychiatry, Psychotherapy and Psychosomatics; Zurich University Hospital for Psychiatry; Zurich Switzerland

5. Translational Medicine Neurosciences; Novartis Pharma AG; Basel Switzerland

6. F Hoffmann-La Roche Ltd.; Basel Switzerland

Publisher

Wiley

Subject

Pharmacology

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