Plasmodium falciparumis dependent onde novomyo-inositol biosynthesis for assembly of GPI glycolipids and infectivity

Author:

MacRae James I.1,Lopaticki Sash2,Maier Alexander G.2,Rupasinghe Thusitha3,Nahid Amsha3,Cowman Alan F.2,McConville Malcolm J.1

Affiliation:

1. Department of Biochemistry and Molecular Biology; Bio21 Institute of Molecular Science and Biotechnology; 30 Flemington Road Melbourne Vic. 3010 Australia

2. Division of Infection and Immunity; The Walter and Eliza Hall Institute of Medical Research; Parkville Vic. 3052 Australia

3. Metabolomics Australia; Bio21 Institute of Molecular Science and Biotechnology; 30 Flemington Road Melbourne Vic. 3010 Australia

Publisher

Wiley

Subject

Molecular Biology,Microbiology

Reference59 articles.

1. Inositol lipids and membrane function in erythrocytes;Allan;Cell Calcium,1982

2. Targeting the lipid metabolic pathways for the treatment of malaria;Ben Mamoun;Drug Dev Res,2010

3. Exploring metabolomic approaches to analyse phospholipid biosynthetic pathways in Plasmodium;Besteiro;Parasitology,2010

4. Host targeting of virulence determinants and phosphoinositides in blood stage malaria parasites;Bhattacharjee;Trends Parasitol,2012a

5. Endoplasmic reticulum PI(3)P lipid binding targets malaria proteins to the host cell;Bhattacharjee;Cell,2012b

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