Different genotypes of a functional polymorphism of theTSHRgene are associated with the development and severity of Graves' and Hashimoto's diseases
Author:
Affiliation:
1. Department of Biomedical Informatics, Division of Health Sciences; Osaka University Graduate School of Medicine; Suita; Japan
2. Department of Laboratory Medicine; Osaka University Graduate School of Medicine; Suita; Japan
Publisher
Wiley
Subject
Genetics,Biochemistry,Immunology,General Medicine,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/tan.12190/fullpdf
Reference5 articles.
1. Associations between autoimmune thyroid disease prognosis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, FCRL3, and ZFAT, previously revealed in genome-wide association studies;Inoue;J Clin Immunol,2012
2. Genetics of thyroid autoimmunity and the role of the TSHR;Brand;Mol Cell Endocrinol,2010
3. The thyrotropin receptor autoantigen in Graves disease is the culprit as well as the victim;Chen;J Clin Invest,2003
4. Thyroid stimulating hormone receptor (TSHR) intron 1 variants are major risk factors for Graves' disease in three European Caucasian cohorts;Ploski;PLoS One,2010
5. Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease;Brand;Hum Mol Genet,2009
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