Irritative potency of selected wound antiseptics in the hen's egg test on chorioallantoic membrane to predict their compatibility to wounds

Author:

Harnoss Julian Camill1ORCID,Elrub Qasim Mahmoud Abu2,Jung Jin-On1,Koburger Torsten3,Assadian Ojan4,Dissemond Joachim5,Baguhl Romy2,Papke Roald2,Kramer Axel2,

Affiliation:

1. Department of General, Visceral and Transplantation Surgery and Study Center of the German Surgical Society; University Hospital Heidelberg; Heidelberg Germany

2. Institute of Hygiene and Environmental Medicine, University Medicine Greifswald; Greifswald Germany

3. Hygiene-North GmbH; Greifswald Germany

4. Department of Infection Control and Hospital Epidemiology; Medical University of Vienna, Vienna General Hospital; Vienna Austria

5. Department of Dermatology, Venereology and Allergology; University Hospital Essen; Essen Germany

Publisher

Wiley

Subject

Dermatology,Surgery

Reference29 articles.

1. Consensus on wound antisepsis: update 2018;Kramer;Skin Pharmacol Physiol,2018

2. Wound cleansing, topical antiseptics and wound healing;Atiyeh;Int Wound J,2009

3. Evaluation of the tissue toxicity of antiseptics by the hen's egg test on the chorioallantoic membrane (HETCAM);Marquardt;Eur J Med Res,2010

4. Interlaboratory assessment of alternatives to the Draize eye irritation test in Germany;Spielmann;Toxicol In Vitro,1991

5. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membrane;Draize;J Pharmacol Exp,1944

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