Identification of a novel compound targeting the nuclear export of influenza A virus nucleoprotein

Author:

Huang Feng1234,Chen Jingliang234,Zhang Junsong234,Tan Likai234,Lu Gui5,Luo Yongjie5,Pan Ting234,Liang Juanran234,Li Qianwen234,Luo Baohong234,Zhang Hui234ORCID,Lu Gen1

Affiliation:

1. Department of Respiration; Affiliated Guangzhou Women and Children's Hospital; Zhongshan School of Medicine; Sun Yat-Sen University; Guangzhou China

2. Institute of Human Virology; Zhongshan School of Medicine; Sun Yat-sen University; Guangzhou China

3. Key Laboratory of Tropical Disease Control of Ministry of Education; Zhongshan School of Medicine; Sun Yat-sen University; Guangzhou China

4. Guangdong Engineering Research Center for Antimicrobial Agent and Immunotechnology; Zhongshan School of Medicine; Sun Yat-sen University; Guangzhou China

5. Institute of Medicinal Chemistry; School of Pharmaceutical Sciences; Sun Yat-sen University; Guangzhou China

Funder

Introduction of Innovative R&D Team Program of Guangdong Province

National Natural Science Foundation of China

National Special Research Program for Important Infectious Diseases

Program for the 12th Five-year Plan

Joint-innovation Program in Healthcare for Special Scientific Research Projects of Guangzhou

Collaborative Research Grant of CAS Key Laboratory of Molecular Virology & Immunology, Institute Pasteur of Shanghai, Chinese Academy of Sciences

General Projects of Guangzhou Scientific Research

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference48 articles.

1. At the centre: influenza A virus ribonucleoproteins;Eisfeld;Nat Rev Microbiol,2015

2. The annual impact of seasonal influenza in the US: measuring disease burden and costs;Molinari;Vaccine,2007

3. The global impact of influenza on morbidity and mortality;Simonsen;Vaccine,1999

4. Influenza virus resistance to antiviral therapy;Vries;Adv Pharmacol,2013

5. A designer drug against influenza: the NA inhibitor oseltamivir (Tamiflu);Oxford;Expert Rev Anti Infect Ther,2003

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