SRR intronic variation inhibits expression of its neighbouring SMG6 gene and protects against temporal lobe epilepsy

Author:

Tao Hua12ORCID,Zhou Xu3,Xie Qian4,Ma Zhonghua5,Sun Fuhai6,Cui Lili2,Cai Yujie2,Ma Guoda2,Fu Jiawu1,Liu Zhou2,Li You2,Zhou Haihong1,Zhao Jianghao1,Chen Yanyan2,Mai Hui1,Chen Ying7,Chen Jun1,Qi Wei1,Sun Chaowen1,Zhao Bin2,Li Keshen89

Affiliation:

1. Department of Neurology; Affiliated Hospital of Guangdong Medical University; Zhanjiang Guangdong China

2. Guangdong Key Laboratory of Age-related Cardiac and Cerebral Diseases; Guangdong Medical University; Zhanjiang Guangdong China

3. Clinical Research Center; Guangdong Medical University; Zhanjiang Guangdong China

4. Emergency Department; Affiliated Hospital of Guangdong Medical University; Zhanjiang Guangdong China

5. Department of Neurology; Beijing Tongren Hospital; Capital Medical University; Beijing China

6. Department of Neurology; the First People's Hospital of Pingdingshan; Pingdingshan Hebei China

7. Department of Neurology; Central People's Hospital of Zhanjiang; Zhanjiang Guangdong China

8. Institute of Neurology; Guangdong Medical University; Zhanjiang Guangdong China

9. Stroke Center; Neurology& Neurosurgery Division; Clinical Medicine Research Institute & the First Affiliated Hospital, Jinan University; Guangzhou Guangdong China

Funder

China Postdoctoral Science Foundation

National Nature Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference36 articles.

1. Intractable epilepsy: management and therapeutic alternatives;Schuele;Lancet Neurol,2008

2. Prevalence and incidence of drug-resistant mesial temporal lobe epilepsy in the United States;Asadi-Pooya;World Neurosurg,2016

3. Current management and surgical outcomes of medically intractable epilepsy;Ramey;Clin Neurol Neurosurg,2013

4. Temporal epilepsy: clinical, diagnostic and therapeutic aspects;Tellez-Zenteno;Rev Neurol,2013

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