Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κ B DNA-binding activity

Author:

Lin Yung-Wei12,Lee Liang-Ming2,Lee Wei-Jiunn34,Chu Chih-Ying1,Tan Peng1,Yang Yi-Chieh5,Chen Wei-Yu6,Yang Shun-Fa78,Hsiao Michael9,Chien Ming-Hsien14

Affiliation:

1. Graduate Institute of Clinical Medicine; Taipei Medical University; Taipei Taiwan

2. Department of Urology; Wan Fang Hospital; Taipei Medical University; Taipei Taiwan

3. Department of Urology; School of Medicine; College of Medicine; Taipei Medical University; Taipei Taiwan

4. Department of Medical Research; Wan Fang Hospital; Taipei Medical University; Taipei Taiwan

5. Graduate Institute of Oncology; College of Medicine; National Taiwan University; Taipei Taiwan

6. Department of Pathology; Wan Fang Hospital; Taipei Medical University; Taipei Taiwan

7. Institute of Medicine; Chung Shan Medical University; Taichung Taiwan

8. Department of Medical Research; Chung Shan Medical University Hospital; Taichung Taiwan

9. Genomics Research Center; Academia Sinica; Taipei Taiwan

Funder

Taipei Medical University

Publisher

Wiley

Subject

Endocrinology

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