Melatonin relieves neuropathic allodynia through spinal MT2-enhanced PP2Ac and downstream HDAC4 shuttling-dependent epigenetic modification of hmgb1 transcription

Author:

Lin Tzer-Bin123,Hsieh Ming-Chun45,Lai Cheng-Yuan46,Cheng Jen-Kun47,Wang Hsueh-Hsiao4,Chau Yat-Pang4,Chen Gin-Den8,Peng Hsien-Yu4

Affiliation:

1. Department of Physiology; School of Medicine; College of Medicine; Taipei Medical University; Taipei Taiwan

2. Graduate Institute of Basic Medical Science; College of Medicine; China Medical University; Taichung Taiwan

3. Department of Biotechnology; Asia University; Taichung Taiwan

4. Department of Medicine; Mackay Medical College; New Taipei Taiwan

5. Department of Physiology; College of Medicine; National Taiwan University; Taipei Taiwan

6. Department of Veterinary Medicine; College of Veterinary Medicine; National Chung-Hsing University; Taichung Taiwan

7. Department of Anesthesiology; Mackay Memorial Hospital; Taipei Taiwan

8. Department of Obstetrics and Gynecology; Chung-Shan Medical University Hospital; Chung-Shan Medical University; Taichung Taiwan

Funder

National Science Council

Mackay Memorial Hospital

Department of Medicine, Mackay Medical College

Taipei Medical University

Saint Paul's Hospital

Publisher

Wiley

Subject

Endocrinology

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