Switching from body surface area-based to fixed dosing for the investigational proteasome inhibitor ixazomib: a population pharmacokinetic analysis

Author:

Gupta Neeraj1,Zhao Yuan1,Hui Ai-Min2,Esseltine Dixie-Lee2,Venkatakrishnan Karthik1

Affiliation:

1. Clinical Pharmacology; Takeda Pharmaceuticals International Co; Cambridge MA USA

2. Oncology Clinical Research; Takeda Pharmaceuticals International Co; Cambridge MA USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference45 articles.

1. Proteasome inhibitors in multiple myeloma: 10 years later;Moreau;Blood,2012

2. Millennium: The Takeda Oncology Company VELCADE® (bortezomib) for injection. Prescribing information 2013 http://www.velcade.com/files/PDFs/VELCADE_PRESCRIBING_INFORMATION.pdf

3. Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study;Moreau;Lancet Oncol,2011

4. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma;Richardson;N Engl J Med,2005

5. Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma;San Miguel;N Engl J Med,2008

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