Huntington's disease: From basic science to therapeutics

Author:

Cepeda Carlos1ORCID,Tong Xiao-Ping2ORCID

Affiliation:

1. Intellectual and Developmental Disabilities Research Center; David Geffen School of Medicine; University of California Los Angeles; Los Angeles CA USA

2. Discipline of Neuroscience and Department of Anatomy and Physiology; Shanghai Jiao Tong University School of Medicine; Shanghai China

Publisher

Wiley

Subject

Pharmacology (medical),Physiology (medical),Psychiatry and Mental health,Pharmacology

Reference16 articles.

1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes;The Huntington's Disease Collaborative Research Group;Cell,1993

2. Excitotoxic injury of the neostriatum: a model for Huntington's disease;DiFiglia;Trends Neurosci,1990

3. Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect;Levine;Trends Neurosci,2004

4. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice;Mangiarini;Cell,1996

5. Wild-type huntingtin plays a role in brain development and neuronal survival;Reiner;Mol Neurobiol,2003

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