Combination Bacillus Calmette-Guérin and indoleamine 2,3-dioxygenase 1 inhibitor therapy of murine orthotopic bladder cancer

Author:

Lee Sze Han1,Mahendran Ratha2,Tham Sin Mun23,Thamboo Thomas Paulraj4,Kioh Dorinda Yan Qin1,Tang Lloyd Wei Tat1,Chiong Edmund23,Esuvaranathan Kesavan23,Chan Eric Chun Yong1ORCID

Affiliation:

1. Department of Pharmacy; National University of Singapore; Singapore City Singapore

2. Department of Surgery; National University of Singapore; Singapore City Singapore

3. Department of Urology; National University Hospital; Singapore City Singapore

4. Department of Pathology; National University Hospital; Singapore City Singapore

Funder

National University Health System (NUHS) Innovation Grant

Publisher

Wiley

Subject

Urology

Reference7 articles.

1. Management of BCG failures in superficial bladder cancer: a review;Witjes;Eur Urol,2006

2. Role of Th1 and Th2 cytokines in BCG-induced IFN-γ production: cytokine promotion and simulation of BCG effect;Luo;Cytokine,2003

3. Targeting the IDO1/TDO2-KYN-AhR pathway for cancer immunotherapy - challenges and opportunities;Cheong;Trends Pharmacol Sci,2018

4. A murine orthotopic bladder tumor model and tumor detection system;Tham;J Vis Exp,2017

5. Bacille-Calmette-Guerin non-responders: how to manage;Von Rundstedt;Transl Androl Urol,2015

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