Antibiotic prophylaxis in neutropenic children with acute leukemia: Do the presently available data really support this practice?

Author:

Calitri Carmelina1ORCID,Ruberto Eliana2,Castagnola Elio3ORCID

Affiliation:

1. Pediatric Unit; Ospedale Cardinal Massaia; Asti Italy

2. Department of Translational Medical Science, Section of Pediatrics; Università di Napoli Federico II; Napoli Italy

3. Infectious Diseases Unit; IRCCS Istituto Giannina Gaslini; Genova Italy

Publisher

Wiley

Subject

Hematology,General Medicine

Reference51 articles.

1. Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy;Gafter-Gvili;Cochrane Database Syst Rev,2012

2. When should an effective treatment be used? Derivation of the threshold number needed to treat and the minimum event rate for treatment;Sinclair;J Clin Epidemiol,2001

3. A multicenter, randomized, double blind placebo-controlled trial of amoxicillin/clavulanate for the prophylaxis of fever and infection in neutropenic children with cancer;Castagnola;Pediatr Infect Dis J,2003

4. Prophylactic first-line antibiotics reduce infectious fever and shorten hospital stay during chemotherapy-induced agranulocytosis in childhood acute myeloid leukemia;Feng;Acta Haematol,2014

5. Antibacterial prophylaxis with trimethoprim-sulfamethoxazole during induction treatment for acute lymphoblastic leukemia;Schrøder;Dan Med Bull,2001

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