Genome‐wide association studies of exacerbations in children using long‐acting beta2‐agonists

Author:

Slob Elise M. A.12ORCID,Richards Levi B.1ORCID,Vijverberg Susanne J. H.123,Longo Cristina1,Koppelman Gerard H.45,Pijnenburg Mariëlle W. H.6,Bel Elisabeth H. D.1,Neerincx Anne H.1,Herrera Luis Esther7,Perez‐Garcia Javier7,Tim Chew Fook8,Yie Sio Yang8,Andiappan Anand K.89,Turner Steve W.10ORCID,Mukhopadhyay Somnath1112,Palmer Colin N. A.12,Hawcutt Daniel1314,Jorgensen Andrea L.15,Burchard Esteban G.1617,Hernandez‐Pacheco Natalia7,Pino‐Yanes Maria7181920ORCID,Maitland‐van der Zee Anke H.123

Affiliation:

1. Department of Respiratory Disease Amsterdam University Medical Centers University of Amsterdam Amsterdam The Netherlands

2. Pediatric Respiratory Medicine Emma Children's Hospital Amsterdam UMC Amsterdam The Netherlands

3. Division of Pharmacoepidemiology and Clinical Pharmacology, Faculty of Science Utrecht University Utrecht Netherlands

4. Department of Paediatric Pulmonology & Paediatric Allergology University Medical Center Groningen Beatrix Children's Hospital University of Groningen Groningen The Netherlands

5. University Medical Center Groningen Groningen Research Institute for Asthma & COPD (GRIAC) University of Groningen Groningen The Netherlands

6. Division of Respiratory Medicine and Allergology Department of Paediatrics Erasmus MC ‐ Sophia University Medical Center Rotterdam Rotterdam The Netherlands

7. Genomics and Health Group Department of Biochemistry, Microbiology, Cell Biology and Genetics Universidad de La Laguna Santa Cruz de Tenerife Spain

8. Singapore Immunology Network (SIgN) Agency for Science, Technology and Research (A*STAR) Singapore Singapore

9. Department of Biological Sciences National University of Singapore Singapore Singapore

10. Department of Child Health University of Aberdeen Aberdeen UK

11. Academic Department of Paediatrics Royal Alexandra Children's Hospital Brighton and Sussex Medical School Brighton UK

12. Population Pharmacogenetics Group Biomedical Research Institute Ninewells Hospital and Medical School University of Dundee Dundee UK

13. Department of Women's and Children's Health University of Liverpool Liverpool UK

14. NIHR Alder Hey Clinical Research Facility Alder Hey Children's Hospital Liverpool UK

15. Department of Health Data Science University of Liverpool Liverpool UK

16. Department of Medicine University of California San Francisco San Francisco CA USA

17. Department of Bioengineering and Therapeutic Sciences University of California San Francisco San Francisco CA USA

18. Research Unit Hospital Universitario N.S. de Candelaria Universidad de La Laguna Santa Cruz de Tenerife Spain

19. Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES) Instituto de Salud Carlos III Madrid Spain

20. Instituto de Tecnologías Biomédicas (ITB) Universidad de La Laguna Santa Cruz de Tenerife Spain

Funder

American Asthma Foundation

National Institute on Minority Health and Health Disparities

European Social Fund

Publisher

Wiley

Subject

Immunology,Immunology and Allergy,Pediatrics, Perinatology, and Child Health

Reference65 articles.

1. Global INitiative for Asthma.Global Strategy for Asthma Management and Prevention(2019 Update).2019;www.gina.org. Accessed 31‐10‐2019 2019.C:\amc.intra\data\group\diva\amc.intra\data\group\diva\Longziekten_Research\PiCA\LABA GWAS\Draft LABA exacerbations and night time awakenings\Results\www.gina.org

2. Step-up Therapy for Children with Uncontrolled Asthma Receiving Inhaled Corticosteroids

3. Budesonide/Formoterol Combination Therapy as Both Maintenance and Reliever Medication in Asthma

4. Budesonide/Formoterol in a Single Inhaler for Maintenance and Relief in Mild-to-Moderate Asthma

5. Ciclesonide versus other inhaled steroids for chronic asthma in children and adults;Manning P;Cochrane Database Syst Rev,2008

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