Management of anaphylaxis due to COVID‐19 vaccines in the elderly

Author:

Bousquet Jean123ORCID,Agache Ioana4ORCID,Blain Hubert5,Jutel Marek67,Ventura Maria Teresa8,Worm Margitta1ORCID,Del Giacco Stefano9,Benetos Athanasios10,Bilo Beatrice Maria1112,Czarlewski Wienczyslawa13,Abdul Latiff Amir Hamzah14,Al‐Ahmad Mona1516ORCID,Angier Elizabeth17,Annesi‐Maesano Isabella18ORCID,Atanaskovic‐Markovic Marina19ORCID,Bachert Claus20212223ORCID,Barbaud Annick2425,Bedbrook Anna14,Bennoor Kazi S.26,Berghea Elena Camelia2728,Bindslev‐Jensen Carsten29,Bonini Sergio30ORCID,Bosnic‐Anticevich Sinthia3132,Brockow Knut33ORCID,Brussino Luisa34,Camargos Paulo35,Canonica G. Walter3637ORCID,Cardona Victoria3839ORCID,Carreiro‐Martins Pedro4041ORCID,Carriazo Ana42,Casale Thomas43,Caubet Jean‐Christoph44ORCID,Cecchi Lorenzo45ORCID,Cherubini Antonio46,Christoff George47,Chu Derek K.48,Cruz Alvaro A.49ORCID,Dokic Dejan50,El‐Gamal† Yehia51,Ebisawa Motohiro52ORCID,Eberlein Bernadette33,Farrell John53,Fernandez‐Rivas Montserrat54,Fokkens Wytske J.5556,Fonseca Joao A.5758,Gao Yadong59,Gavazzi Gaëtan60,Gawlik Radoslaw61,Gelincik Asli62ORCID,Gemicioğlu Bilun63,Gotua Maia64ORCID,Guérin Olivier65,Haahtela Tari66ORCID,Hoffmann‐Sommergruber Karin67,Hoffmann Hans Jürgen6869,Hofmann Maja1,Hrubisko Martin70,Illario Maddalena71,Irani Carla72,Ispayeva Zhanat73,Ivancevich Juan Carlos74,Julge Kaja75,Kaidashev Igor76,Khaitov Musa77ORCID,Knol Edward78,Kraxner Helga79,Kuna Piotr80,Kvedariene Violeta8182,Lauerma Antti83,Le Lan T. T.84,Le Moing Vincent85,Levin Michael86ORCID,Louis Renaud87,Lourenco Olga88ORCID,Mahler Vera89,Martin Finbarr C.90,Matucci Andrea91,Milenkovic Branislava92,Miot Stéphanie5,Montella Emma71,Morais‐Almeida Mario93ORCID,Mortz Charlotte G.29ORCID,Mullol Joaquim9495,Namazova‐Baranova Leyla96,Neffen Hugo97,Nekam Kristof98,Niedoszytko Marek99ORCID,Odemyr Mikaëla100,O’Hehir Robyn E.101ORCID,Okamoto Yoshitaka102,Ollert Markus103104,Palomares Oscar105ORCID,Papadopoulos Nikolaos G.106ORCID,Panzner Petr107ORCID,Passalacqua Giovanni108ORCID,Patella Vincenzo109ORCID,Petrovic Mirko110,Pfaar Oliver111ORCID,Pham‐Thi Nhân112,Plavec Davor113114,Popov Todor A.115,Recto Marysia T.116,Regateiro Frederico S.117118119,Reynes Jacques85,Roller‐Winsberger Regina E.120,Rolland Yves121,Romano Antonino122123,Rondon Carmen124125ORCID,Rottem Menachem126127,Rouadi Philip W.128ORCID,Salles Nathalie129,Samolinski Boleslaw130,Santos Alexandra F.131132133134ORCID,Sarquis Faradiba135,Sastre Joaquin136ORCID,M. G. A. Schols Jos137,Scichilone Nicola138,Sediva Anna139,Shamji Mohamed H.140141ORCID,Sheikh Aziz142,Skypala Isabel143ORCID,Smolinska Sylwia144145,Sokolowska Milena146,Sousa‐Pinto Bernardo5758147,Sova Milan148,Stelmach Rafael149,Sturm Gunter150151,Suppli Ulrik Charlotte152,Todo‐Bom Ana Maria153ORCID,Toppila‐Salmi Sanna66,Tsiligianni Ioanna154155ORCID,Torres Maria156ORCID,Untersmayr Eva157,Urrutia Pereira Marilyn158,Valiulis Arunas159160ORCID,Vitte Joana161162ORCID,Vultaggio Alessandra91,Wallace Dana163,Walusiak‐Skorupa Jolanta164,Wang De‐Yun165,Waserman Susan48,Yorgancioglu Arzu166,Yusuf Osman M.167,Zernotti Mario168,Zidarn Mihaela169,Chivato Tomas170ORCID,Akdis Cezmi A.171ORCID,Zuberbier Torsten1,Klimek Ludger172173ORCID

Affiliation:

1. Department of Dermatology and Allergy Comprehensive Allergy Center Charité Universitätsmedizin Berlin Humboldt‐Universität zu Berlin Berlin Institute of Health Berlin Germany

2. University Hospital Montpellier France

3. MACVIA‐France Montpellier France

4. Faculty of Medicine Transylvania University Brasov Romania

5. Department of Geriatrics Montpellier University Hospital Montpellier France

6. Department of Clinical Immunology Wrocław Medical University Wroclaw Poland

7. ALL‐MED Medical Research Institute Wrocław Poland

8. University of Bari Medical School Unit of Geriatric Immunoallergology Bari Italy

9. Department of Medical Sciences and Public Health Unit of Allergy and Clinical Immunology University Hospital "Duilio Casula" University of Cagliari Cagliari Italy

10. Department of Geriatrics CHRU de Nancy and Inserm DCAC Université de Lorraine Nancy France

11. Allergy Unit Department of Clinical and Molecular Sciences Università Politecnica delle Marche Ancona Italy

12. Department of Internal Medicine University Hospital Ospedali Riuniti di Ancona Ancona Italy

13. Medical Consulting Czarlewski Levallois France

14. Department of Pediatrics Allergy & Immunology Centre Pantai Hospital Universiti Putra Malaysia Teaching Hospital Kuala Lumpur Malaysia

15. Microbiology Department Faculty of Medicine Kuwait University Kuwait City Kuwait

16. Department of Allergy Al‐Rashed Allergy Center Kuwait City Kuwait

17. Primary Care and Population Sciences University of Southampton Southampton UK

18. Institut Desbrest d'Epidémiologie et Santé Publique (IDESP) INSERM et Université de Montpellier Montpellier France

19. Faculty of Medicine University Children's Hospital University of Belgrade Belgrade Serbia

20. Upper Airways Research Laboratory ENT Department Ghent University Hospital Ghent Belgium

21. International Airway Research Center Sun Yat‐sen University First Affiliated Hospital Guangzou China

22. Division of ENT Diseases CLINTEC, Karolinska Institutet Stockholm Sweden

23. Department of ENT Diseases Karolinska University Hospital Stockholm Sweden

24. Division of Service de Dermatologie et Allergologie Hôpital Tenon Paris France

25. Division of Equipe PEPITES Sorbonne Université Institut Pierre Louis d'Epidémiologie et de Santé Publique Paris France

26. Department of Respiratory Medicine National Institute of Diseases of the Chest and Hospital Dhaka Bangladesh

27. Allergology and Clinical Immunology Carol Davila University of Medicine and Pharmacy Bucharest Romania

28. Clinical Emergency Hospital for Children MS Curie Bucharest Romania

29. Department of Dermatology and Allergy Centre Odense University Hospital Odense Research Center for Anaphylaxis (ORCA) Odense Denmark

30. Institute of Translational Pharmacology Italian National Research Council Rome Italy

31. Woolcock Institute of Medical Research University of Sydney Glebe NSW Australia

32. Woolcock Emphysema Centre Sydney Local Health District Glebe NSW Australia

33. Department of Dermatology and Allergy Biederstein School of Medicine Technical University of Munich Munich Germany

34. Department of Medical Sciences Allergy and Clinical Immunology Unit University of Torino & Mauriziano Hospital Torino Italy

35. Department of Pediatrics Medical School Federal University of Minas Gerais Belo Horizonte Brazil

36. Department of Biomedical Sciences, Humanitas University Milan Italy

37. IRCCS Humanitas Research Hospital, Personalized Medicine, Asthma and Allergy Milan Italy

38. Allergy Section Department of Internal Medicine Hospital Vall d'Hebron Barcelona Spain

39. ARADyAL Research Network Barcelona Spain

40. Serviço de Imunoalergologia, Hospital de Dona Estefânia Centro Hospitalar de Lisboa Central Lisbon Portugal

41. Faculdade de Ciências Médicas (FCM) CEDOC Universidade Nova de Lisboa Lisbon Portugal

42. Regional Ministry of Health of Andalusia Seville Spain

43. Division of Allergy/Immunology University of South Florida Tampa FL USA

44. Pediatric Allergy Unit Department of Child and Adolescent Geneva University Hospital Geneva Switzerland

45. SOS Allergology and Clinical Immunology USL Toscana Centro Prato Italy

46. Geriatria, Accettazione Geriatrica e Centro di Ricerca per l’invecchiamento IRCCS INRCA Ancona Italy

47. Faculty of Public Health Medical University Sofia Bulgaria

48. Department of Medicine and Health Research Methods, Evidence & Impact McMaster University Hamilton ON Canada

49. Fundação ProAR Federal University of Bahia and GARD/WHO Planning Group Salvador BA Brazil

50. Medical Faculty University Clinic of Pulmology and Allergy Skopje Republic of Macedonia

51. Pediatric Allergy and Immunology Unit Children’s Hospital Ain Shams University Cairo Egypt

52. Clinical Research Center for Allergy and Rheumatology NHO Sagamihara National Hospital Sagamihara Japan

53. LANUA International Healthcare Consultancy Down UK

54. Allergy Department Hospital Clínico San Carlos UCM IdISSC Madrid Spain

55. Department of Otorhinolaryngology Academic Medical Centers AMC Amsterdam The Netherland

56. EUFOREA Brussels Belgium

57. Faculdade de Medicina CINTESIS Center for Health Technology and Services Research Universidade do Porto Porto Portugal

58. Allergy Unit CUF Porto Porto Portugal

59. Department of Allergology Zhongnan Hospital of Wuhan University Wuhan China

60. Service Gériatrie Clinique Centre Hospitalo‐Universitaire Grenoble‐Alpes GREPI (TIMC‐IMAG, CNRS 5525 Université Grenoble‐Alpes Grenoble France

61. Department of Internal Medicine, Allergy and Clin Immunology Silesian University of Medicine Katowice Poland

62. Division of Immunology and Allergic Diseases Department of Internal Medicine Istanbul Faculty of Medicine Istanbul University Istanbul Turkey

63. Department of Pulmonary Diseases Istanbul University‐Cerrahpasa Cerrahpasa Faculty of Medicine Istanbul Turkey

64. Center of Allergy and Immunology Georgian Association of Allergology and Clinical Immunology Tbilisi Georgia

65. Service de Gériatrie CHRU Nice France

66. Skin and Allergy Hospital Helsinki University Hospital University of Helsinki University Helsinki Finland

67. Institute of Pathophysiology and Allergy Research Center of Pathophysiology Infectiology and Immunology Medical University of Vienna Vienna Austria

68. Department of Respiratory Diseases and Allergy Aarhus University Hospital Aarhus Denmark

69. Institute of Clinical Medicine Aarhus University Aarhus Denmark

70. Department of Clinical Immunology and Allergy Oncology Institute of St Elisabeth Bratislava Slovakia

71. Department of Public Health and Research and Development Unit Federico II University & Hospital Naples Italy

72. Department of Internal Medicine and Infectious Diseases St Joseph University Hotel Dieu de France Hospital Beirut Lebanon

73. President of Kazakhstan Association of Allergology and Clinical Immunology Department of Allergology and Clinical Immunology Kazakh National Medical University Almaty Kazakhstan

74. Servicio de Alergia e Immunologia Clinica Santa Isabel Buenos Aires Argentina

75. Tartu University Institute of Clinical Medicine Children's Clinic Tartu Estonia

76. Ukrainina Medical Stomatological Academy Poltava Ukraine

77. National Research Center Institute of Immunology, Federal Medicobiological Agency, Laboratory of Molecular Immunology Moscow Russia

78. Departments of Immunology and Dermatology/Allergology University Medical Center Utrecht The Netherlands

79. Department of Otorhinolaryngology, Head and Neck Surgery Semmelweis University Budapest Hungary

80. Division of Internal Medicine, Asthma and Allergy Barlicki University Hospital Medical University of Lodz Lodz Poland

81. Institute of Biomedical Sciences Department of Pathology Faculty of Medicine Vilnius University Vilnius Lithuania

82. Institute of Clinical Medicine Clinic of Chest Diseases and Allergology Faculty of Medicine Vilnius University Vilnius Lithuania

83. Department of Dermatology and Allergology University of Helsinki and Helsinki University Helsinki Finland

84. University of Medicine and Pharmacy Hochiminh City Vietnam

85. Department of Infectiology Montpellier University Hospital Montpellier France

86. Division Paediatric Allergology University of Cape Town Cape Town South Africa

87. Department of Pulmonary Medicine CHU Sart‐Tilman GIGA I3 Research Group Liege Belgium

88. Faculty of Health Sciences CICS – UBI Health Sciences Research Centre University of Beira Interior Covilhã Portugal

89. Paul‐Ehrlich‐Institut Langen Germany

90. Emeritus Geriatrician and Professor of Medical Gerontology Population Health Sciences I King’s College London London UK

91. Immunoallergology Unit Careggi University Hospital Florence Italy

92. Clinic for Pulmonary Diseases Clinical Center of Serbia Faculty of Medicine University of Belgrade Serbian Association for Asthma and COPD Belgrade Serbia

93. Allergy Center CUF Descobertas Hospital Lisbon Portugal

94. Rhinology Unit & Smell Clinic ENT Department Hospital Clínic Barcelona Spain

95. Clinical & Experimental Respiratory Immunoallergy IDIBAPS CIBERES University of Barcelona Barcelona Spain

96. Pediatrics and Child Health Research Institute Central Clinical Hospital of the Russian Academy of Sciences Russian National Research Medical University Moscow Russia

97. Director of Center of Allergy, Immunology and Respiratory Diseases Santa Fe Argentina

98. Hospital of the Hospitaller Brothers in Buda Budapest Hungary

99. Department of Allergology Medical University of Gdańsk Gdańsk Poland

100. EFA European Federation of Allergy and Airways Diseases Patients’ Associations Brussels Belgium

101. Department of Allergy, Immunology and Respiratory Medicine Central Clinical School Monash University Alfred Health Melbourne Vic. Australia

102. Department of Otorhinolaryngology Chiba University Hospital Chiba Japan

103. Department of Infection and Immunity Luxembourg Institute of Health Esch‐sur‐Alzette Luxembourg

104. Department of Dermatology and Allergy Center Odense Research Center for Anaphylaxis Odense University Hospital University of Southern Denmark Odense Denmark

105. Department of Biochemistry and Molecular Biology School of Chemistry Complutense University of Madrid Madrid Spain

106. Allergy Department 2nd Pediatric Clinic Athens General Children's Hospital "P&A Kyriakou” University of Athens Athens Greece

107. Department of Immunology and Allergology Faculty of Medicine and Faculty Hospital in Pilsen Charles University in Prague Pilsen Czech Republic

108. Allergy and Respiratory Diseases Ospedale Policlino San Martino ‐University of Genoa Genoa Italy

109. Division of Allergy and Clinical Immunology Department of Medicine Agency of Health ASL Salerno, "Santa Maria della Speranza" Hospital Salerno Italy

110. Department of Internal Medicine and Paediatrics Section of Geriatrics Faculty of Medicine and Health Sciences Ghent University Ghent Belgium

111. Department of Otorhinolaryngology, Head and Neck Surgery Section of Rhinology and Allergy University Hospital Marburg Philipps‐Universität Marburg Marburg Germany

112. Ecole polytechnique Palaiseau IRBA (Institut de Recherche bio‐Médicale des Armées) Bretigny France

113. Children’s Hospital Srebrnjak Zagreb Croatia

114. School of Medicine University J.J. Strossmayer Osijek Croatia

115. University Hospital Sv Ivan Rilski’ Sofia Bulgaria

116. Asian Hospital and Medical Center Manilla Philippines

117. Allergy and Clinical Immunology Unit Centro Hospitalar e Universitário de Coimbra Coimbra Portugal

118. Institute of Immunology Faculty of Medicine University of Coimbra Coimbra Portugal

119. Faculty of Medicine ICBR ‐ Coimbra Institute for Clinical and Biomedical Research CIBB University of Coimbra Coimbra Portugal

120. Medical University of Graz Graz Austria

121. Gérontopôle de Toulouse INSERM 1027 Toulouse France

122. Oasi Research Institute‐IRCCS Troina Italy

123. Fondazione Mediterranea GB Morgagni Catania Italy

124. Allergy Unit Hospital Regional Universitario de Malaga Malaga Spain

125. Allergy Research Group Instituto de Investigación Biomedica de Malaga‐IBIMA and ARADyAL Malaga Spain

126. Division of Allergy Asthma and Clinical Immunology Emek Medical Center Afula Israel

127. Rappaport Faculty of Medicine Technion‐Israel Institute of Technology Haifa Israel

128. Department of Otolaryngology‐Head and Neck Surgery Eye and Ear University Hospital Beirut Lebanon

129. Société Française de Gériatrie et Gérontologie Paris France

130. Department of Prevention of Environmental Hazards, Allergology & Immunology Medical University of Warsaw Warsaw Poland

131. Department of Women and Children's Health (Paediatric Allergy) School of Life Course Sciences Faculty of Life Sciences and Medicine King's College London London UK

132. Peter Gorer Department of Immunobiology School of Immunology and Microbial Sciences Faculty of Life Sciences and Medicine King's College London London UK

133. Children's Allergy Service Evelina London Children's Hospital Guy'sand St Thomas Hospital London UK

134. Asthma UK Centre for Allergic Mechanisms in Asthma London UK

135. Asthma Reference Center School of Medicine of Santa Casa de Misericórdia of Vitória Espírito Santo Brazil

136. Faculty of Medicine Fundacion Jimenez Diaz CIBERES Autonoma University of Madrid Madrid Spain

137. Department of Health Services Research Department of Family Medicine Caphri ‐ Care and Public Health Research Institute Maastricht University Maastrich NL USA

138. PROMISE Department University of Palermo Palermo Italy

139. Department of Immunology Second Faculty of Medicine Charles University and Motol University Hospital Prague Czech Republic

140. Immunomodulation and Tolerance Group Imperial College London London UK

141. Allergy and Clinical Immunology Imperial College London London UK

142. Usher Institute The University of Edinburgh Edinburgh UK

143. Royal Brompton and Harefield NHS Foundation Trust London UK

144. Department of Clinical Immunology Wroclaw Medical University Wroclaw Poland

145. ALL‐MED" Medical Research Institute Wroclaw Poland

146. Christine Kühne ‐ Center for Allergy Research and Education CK‐CARE Davos Switzerland

147. MEDCIDS – Department of Community Medicine, Information and Health Decision Sciences Faculty of Medicine University of Porto Porto Portugal

148. Department of Respiratory Medicine University Hospital Olomouc Olomouc Czech Republic

149. Pulmonary Division Heart Institute (InCor Hospital da Clinicas da Faculdade de Medicina da Universidade de Sao Paulo Sao Paulo Brazil

150. Department of Dermatology and Venerology Medical University of Graz Graz Austria

151. Austria Outpatient Allergy Clinic Reumannplatz Vienna Austria

152. Department of Respiratory Medicine Copenhagen University Hospital‐Hvidovre Institute of Clinical Medicine University of Copenhagen Copenhagen Denmark

153. Imunoalergologia Centro Hospitalar Universitário de Coimbra and Faculty of Medicine University of Coimbra Coimbra Portugal

154. Health Planning Unit Department of Social Medicine Faculty of Medicine University of Crete Crete Greece

155. International Primary Care Respiratory Group IPCRG Aberdeen UK

156. Allergy Unit Málaga Regional University Hospital‐IBIMA Málaga Spain

157. Institute of Pathophysiology and Allergy Research Center of Pathophysiology, Infectiology and Immunology Medical University of Vienna Vienna Austria

158. Federal University of Pampa Uruguaiana Brazil

159. Faculty of Medicine Vilnius University Institute of Clinical Medicine & Institute of Health Sciences Vilnius Lithuania

160. European Academy of Paediatrics (EAP/UEMS‐SP Brussels Belgium

161. Aix‐Marseille University IRD, APHM MEPHI Marseille France

162. IHU Méditerranée Infection, Marseille and IDESP INSERM University of Montpellier Montpellier France

163. Nova Southeastern University Fort Lauderdale FL USA

164. Department of Occupational Diseases and Environmental Health Nofer Institute of Occupational Medicine Lodz Poland

165. Department of Otolaryngology Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

166. Department of Pulmonary Diseases Faculty of Medicine Celal Bayar University Manisa Turkey

167. The Allergy and Asthma Institute Islamabad Pakistan

168. Universidad Católica de Córdoba Universidad Nacional de Villa Maria Villa Maria Argentina

169. University Clinic of Respiratory and Allergic Diseases Golnik Slovenia

170. School of Medicine University CEU San Pablo Madrid Spain

171. Swiss Institute of Allergy and Asthma Research (SIAF) University of Zurich Davos Switzerland

172. Department of Otolaryngology, Head and Neck Surgery Universitätsmedizin Mainz Mainz Germany

173. Center for Rhinology and Allergology Wiesbaden Germany

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

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