A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption-Reference-Cited by-同舟云学术

A proof of concept using the Ussing chamber methodology to study pediatric intestinal drug transport and age‐dependent differences in absorption

Published:2022-08-12 Issue:10 Volume:15 Page:2392-2402
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clinical Translational Sci

Author:

Streekstra Eva J.¹²^ORCID,Kiss Márton¹,van den Heuvel Jeroen¹,Nicolaï Johan³,van den Broek Petra¹,Botden Sanne M. B. I.⁴^ORCID,Stommel Martijn W. J.⁵,van Rijssel Lara¹,Ungell Anna‐Lena³,van de Steeg Evita²,Russel Frans G. M.¹^ORCID,de Wildt Saskia N.¹⁶^ORCID

Affiliation:

1. Department of Pharmacology and Toxicology Radboud University Medical Center Nijmegen The Netherlands

2. Department of Metabolic Health Research TNO Zeist The Netherlands

3. Development Science UCB Biopharma SRL Braine‐l'Alleud Belgium

4. Department of Pediatric Surgery Radboudumc‐Amalia Children's Hospital Nijmegen The Netherlands

5. Department of Surgery Radboud University Medical Center Nijmegen The Netherlands

6. Intensive Care and Department of Pediatric Surgery Erasmus MC‐Sophia Children's Hospital Rotterdam The Netherlands

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.13368

Reference39 articles.

1. Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review

2. Use of Body Surface Area for Dosing of Vancomycin

3. Developmental Changes in Pharmacokinetics and Pharmacodynamics

4. Preference for pharmaceutical formulation and treatment process attributes

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