Affiliation:
1. Department of Biological Sciences Faculty of Science National University of Singapore Singapore Singapore
Abstract
AbstractBackgroundWe evaluate skin sagging phenotypes (eyebags, droopy eyelids, low eyebrow positioning) using written descriptive scales and photo‐numeric scales. We also study how anti‐ageing interventions and digital screen time influence skin sagging.AimWe compare the two phenotype assessment methods with each other.MethodSkin sagging and personal lifestyle data obtained from 2885 ethnic Chinese young adults from the Singapore/Malaysia cross‐sectional genetics epidemiology study (SMCGES) cohort were collated and compared.ResultsSignificant correlations (p‐value < 0.001) between written descriptive scales and photo‐numeric scales were observed for eyebags (0.25) and eyebrow positioning (0.08). Significant correlations (p‐value < 0.001) were observed after combining both scales for eyebags (0.38), droopy eyelids (0.30), and eyebrow positioning (0.30). Anti‐ageing interventions are associated with delayed progression of eyebags from 18–45 years old, droopy eyelids from 31–45 years old, and eyebrow positioning from 35–40 years old. Significantly lower (p‐value < 0.02) eyebrow positioning is associated with both <1 and 1–3 h of screen time stratified by age.ConclusionWritten descriptive scales provide comparable results to photo‐numeric scales. However, validating and adapting photo‐numeric scales for different populations identifies phenotypes better. Anti‐ageing interventions are beneficial at different age ranges. Screen time is associated with skin sagging in young (18–30 years old) participants.
Funder
National University of Singapore
Biomedical Research Council
Singapore Immunology Network
National Medical Research Council
National Research Foundation
Singapore Food Agency
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