S1 Guideline onychomycosis

Author:

Nenoff Pietro1,Reinel Dieter2,Mayser Peter3,Abeck Dietrich4,Bezold Guntram5,Bosshard Philipp P.6,Brasch Jochen7,Daeschlein Georg8,Effendy Isaak9,Ginter‐Hanselmayer Gabriele10,Gräser Yvonne11,Hamm Gudrun12,Hengge Ulrich13,Hipler Uta‐Christina14,Höger Peter15,Kargl Alexandra16,Kolb‐Mäurer Annette17,Krüger Constanze1,Malisiewicz Bartosz18,Mayer Johannes19,Ott Hagen20,Paasch Uwe21,Schaller Martin22,Uhrlaß Silke1,Zidane Miriam23

Affiliation:

1. Labopart – Medizinische Laboratorien Labor Leipzig‐Mölbis [Labopart – Medical Laboratories, Laboratory Leipzig‐Mölbis] Rötha OT Mölbis Germany

2. Praxis für Dermatologie [Dermatology practice] Hamburg Germany

3. Biebertal Germany

4. Hautzentrum Nymphenburg [Nymphenburg Skin Center] München, Munich Germany

5. Hautarztpraxis Neu‐Ulm [Neu‐Ulm dermatology practice] Neu‐Ulm Germany

6. Dermatologische Klinik Universitätsspital Zürich Universität Zürich [Department of Dermatology, University Hospital Zurich, University of Zurich] Zürich Switzerland

7. Klinik für Dermatologie Venerologie und Allergologie Universitätsklinikum Schleswig‐Holstein Campus Kiel [Department of dermatology venereology and allergology Schleswig‐Holstein University hospital, Kiel campus] Kiel Germany

8. Hautklinik Städtisches Klinikum Dessau [Skin clinic Dessau City Hospital] Dessau Germany

9. Klinik für Dermatologie Venerologie und Allergologie Universitätsklinikum OWL Campus Klinikum Bielefeld, Universität Bielefeld [Department of Dermatology, Venereology and Allergology, University Hospital OWL, Campus Bielefeld, University of Bielefeld] Bielefeld Germany

10. Universitätsklinik für Dermatologie und Venerologie Medizinische Universität Graz [University department of dermatology and venereology Graz Medical University] Graz Austria

11. Charité – Universitätsmedizin Berlin Institut für Mikrobiologie und Infektionsimmunologie Nationales Konsiliarlabor für Dermatophyten [Charité – University Medicine Berlin, Institute of Microbiology and Infection Immunology, National consultant lab for dermatophytes] Berlin Germany

12. Hautarztpraxis Dr. med. Gudrun Hamm [Gudrun Hamm MD dermatology practice] Halle (Saale) Germany

13. Hautzentrum [Skin Center] Prof. Hengge Düsseldorf Germany

14. Klinik für Hautkrankheiten Universitätsklinikum Jena [Skin disease clinic Jena University Hospital] Jena Germany

15. Abteilung Pädiatrische Dermatologie und Allergologie Kath. Kinderkrankenhaus Wilhelmstift [Department of Pediatric Dermatology and Allergology, Catholic Children's Hospital Wilhelmstift] Hamburg Germany

16. Hautärzte am Gasteig München [Dermatologists am Gasteig Munich] Germany

17. Klinik und Poliklinik für Dermatologie Venerologie und Allergologie Universitätsklinikum Würzburg [Department of dermatology venereology and allergology Würzburg University Hospital] Würzburg Germany

18. Klinik für Dermatologie Venerologie und Allergologie Universitätsklinikum Frankfurt [Department of dermatology venereology and allergology Frankfurt University Hospital] Frankfurt am Main Germany

19. Polipraxis AG Herisau Switzerland

20. Abteilung für pädiatrische Dermatologie und Allergologie Kinder‐ und Jugendkrankenhaus auf der Bult [Department of dermatology and allergology Children's and adolescents‘ hospital auf der Bult] Hannover Germany

21. Klinik und Poliklinik für Dermatologie Venerologie und Allergologie Universitätsklinikum Leipzig [Department of dermatology venereology and allergology Leipzig University Hospital] Leipzig Germany

22. Universitäts‐Hautklinik Tübingen Eberhard Karls Universität Tübingen Tübingen Germany

23. Charité – Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt‐Universität zu Berlin Klinik für Dermatologie Venerologie und Allergologie [Department of dermatology venereology and allergology] Division of Evidence‐Based Medicine (dEBM) Berlin Germany

Abstract

SummaryOnychomycosis is a fungal infection of the fingernails and toenails. In Europe, tinea unguium is mainly caused by dermatophytes. The diagnostic workup comprises microscopic examination, culture and/or molecular testing (nail scrapings). Local treatment with antifungal nail polish is recommended for mild or moderate nail infections. In case of moderate to severe onychomycosis, oral treatment is recommended (in the absence of contraindications). Treatment should consist of topical and systemic agents. The aim of this update of the German S1 guideline is to simplify the selection and implementation of appropriate diagnostics and treatment. The guideline was based on current international guidelines and the results of a literature review conducted by the experts of the guideline committee. This multidisciplinary committee consisted of representatives from the German Society of Dermatology (DDG), the German‐Speaking Mycological Society (DMykG), the Association of German Dermatologists (BVDD), the German Society for Hygiene and Microbiology (DGHM), the German Society of Pediatric and Adolescent Medicine (DGKJ), the Working Group for Pediatric Dermatology (APD) and the German Society for Pediatric Infectious Diseases (DGPI). The Division of Evidence‐based Medicine (dEBM) provided methodological assistance. The guideline was approved by the participating medical societies following a comprehensive internal and external review.

Publisher

Wiley

Subject

Dermatology

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