Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes-Reference-Cited by-同舟云学术

Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes

Published:2018-02-27 Issue:3 Volume:154 Page:522-532
ISSN:0019-2805
Container-title:Immunology
language:en
Short-container-title:Immunology

Author:

Yap Jin Yan¹,Wirasinha Rushika C.²,Chan Anna²,Howard Debbie R.¹,Goodnow Christopher C.³⁴,Daley Stephen R.¹²^ORCID

Affiliation:

1. Department of Immunology and Infectious Disease; The John Curtin School of Medical Research; The Australian National University; Canberra ACT Australia

2. Infection and Immunity Programme; Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology; Monash University; Melbourne VIC Australia

3. Immunology Division; Garvan Institute of Medical Research; Sydney NSW Australia

4. St Vincent's Clinical School; University of New South Wales; Sydney NSW Australia

Funder

National Health and Medical Research Council

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/imm.12904/fullpdf

Reference44 articles.

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2. Negative selection by endogenous antigen and superantigen occurs at multiple thymic sites;Douek;Int Immunol,1996

3. Developmental regulation of Foxp3 expression during ontogeny;Fontenot;J Exp Med,2005

4. Rare development of Foxp3+ thymocytes in the CD4+CD8+ subset;Lee;J Immunol,2009

5. The thymic medulla: a unique microenvironment for intercellular self-antigen transfer;Koble;J Exp Med,2009

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