Patients with gastroesophageal reflux disease (both reflux oesophagitis and non‐erosive reflux disease): Prevalence and severity of erosive tooth wear and saliva properties

Author:

Kitasako Yuichi123ORCID,Tanabe Tomohide1,Koeda Mai1,Momma Eri1,Hoshikawa Yoshimasa1,Hoshino Shintaro1,Kawami Noriyuki1,Ikeda Masaomi4,Iwakiri Katsuhiko1

Affiliation:

1. Department of Gastroenterology, Nippon Medical School Graduate School of Medicine Tokyo Japan

2. Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo Japan

3. Dental Clinic, Ministry of Foreign Affairs Tokyo Japan

4. Oral Prosthetic Engineering, Graduate School Tokyo Medical and Dental University Tokyo Japan

Abstract

AbstractBackgroundThe prevalence between erosive tooth wear (ETW) in association with reflux oesophagitis (RO) has been reported. However, the severity of both diseases and the relationship between ETW and non‐erosive reflux disease (NERD) is unclear.ObjectivesThe prevalence and severity of ETW were investigated in RO, NERD and healthy controls.Methods135 patients with RO, 65 with NERD and 40 healthy controls were recruited for this case–control study. A modified tooth wear index was used to evaluate the prevalence and severity of ETW. Salivary secretion and buffer capacity were assessed prior to endoscopy. The prevalence and severity of ETW, saliva properties among each group were analysed using Pearson's chi‐squared test.ResultsA total of 135 cases (56.3%) were categorised as the patient with ETW (55 with mild RO, 49 with severe RO and 31 with NERD). There was a significant relationship between the prevalence of RO and ETW, while there was no significant correlation between the prevalence of NERD and ETW. There was a significant difference related to the severity between RO and ETW. For salivary secretion, there was a significant difference between with and without ETW in patients with mild RO, severe RO and NERD. There was a significant difference between with and without ETW for salivary buffer capacity in patients with mild and severe RO.ConclusionThere was a significant association of the prevalence and severity between RO and ETW. Clinical signs such as ETW and salivary buffer capacity depended on the severity of RO.

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

General Dentistry

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