Efficacy and safety of a hexanic extract of Serenoa repens (Permixon®) for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH): systematic review and meta-analysis of randomised controlled trials and obser

Author:

Vela-Navarrete Remigio1,Alcaraz Antonio2,Rodríguez-Antolín Alfredo3,Miñana López Bernardino4,Fernández-Gómez Jesús M.5,Angulo Javier C.6ORCID,Castro Díaz David7,Romero-Otero Javier3,Brenes Francisco J.8,Carballido Joaquín9,Molero García José Mª10,Fernández-Pro Ledesma Antonio11,Cózar Olmos José Manuel12,Manasanch Dalmau José13ORCID,Subirana Cachinero Isaac14,Herdman Michael15ORCID,Ficarra Vincenzo16ORCID

Affiliation:

1. Emeritus Professor of Urology; Universidad Autónoma de Madrid; Madrid Spain

2. Urology Department; IDIBAPS; Hospital Clínic; Universitat de Barcelona; Barcelona Spain

3. Urology Department; Instituto de Salud Integral del Varón; Fundación Investigación 12 de Octubre; Hospital Universitario 12 de Octubre; Madrid Spain

4. Urology Department; Clínica Universidad de Navarra; Universidad de Navarra; Pamplona, Navarra Spain

5. Urology Department; Hospital Universitario Central de Asturias; Universidad de Oviedo; Oviedo Spain

6. Urology Department; Departamento Clínico; Facultad de Ciencias Biomédicas; Hospital Universitario de Getafe; Universidad Europea de Madrid; Laureate Universities; Getafe Madrid Spain

7. Urology Department; Hospital Universitario de Canarias; Universidad de La Laguna; Tenerife Spain

8. Llefià Primary Care Center; Badalona, Barcelona Spain

9. Urology Department; Hospital Universitario Puerta de Hierro Majadahonda; Madrid Spain

10. San Andrés Primary Care Center; Madrid Spain

11. Menasalbas Primary Care Center; Toledo Spain

12. Urology Department; Complejo Hospitalario Universitario de Granada; Granada Spain

13. Pierre Fabre Ibérica S.A.; Barcelona Spain

14. CIBER Epidemiología y Salud Pública; REGICOR Study Group; IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Grup d'Epidemiologia i Genètica Cardiovasculars (EGEC); Barcelona Spain

15. Insight Consulting and Research; Mataró Spain

16. Department of Urology; University of Messina; Messina Italy

Funder

Pierre Fabre Ibérica, S.A, Barcelona, Spain

Publisher

Wiley

Subject

Urology

Reference67 articles.

1. Male lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH);Roehrborn;Med Clin North Am,2011

2. Quality-of-life impact of lower urinary tract symptom severity: results from the Health Professionals Follow-up Study;Welch;Urology,2002

3. Gravas S Bach T Bachmannn A et al. EAU Guidelines on Management of Non-Neurogenic Male Lower Urinary Tract Symptoms (LUTS) incl. Benign Prostatic Obstruction (BPO), 2016 https://uroweb.org/wp-content/uploads/EAU-Guidelines-Management-of-non-neurogenic-male-LUTS-2016.pdf

4. Serenoa repens for benign prostatic hyperplasia;Tacklind;Cochrane Database Syst Rev,2012

5. Saw palmetto extracts for treatment of benign prostatic hyperplasia;Wilt;JAMA,1998

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