Opioid-induced inhibition of the human 5-HT and noradrenaline transportersin vitro: link to clinical reports of serotonin syndrome

Author:

Rickli Anna1,Liakoni Evangelia2,Hoener Marius C3,Liechti Matthias E1ORCID

Affiliation:

1. Clinical Pharmacology and Toxicology, Department of Biomedicine, Department of Internal Medicine; University Hospital Basel, University of Basel; Basel Switzerland

2. Clinical Pharmacology and Toxicology, Department of General Internal Medicine, Inselspital; Bern University Hospital, University of Bern; Bern Switzerland

3. Neuroscience Research, pRED, Roche Innovation Center Basel; F. Hoffmann-La Roche Ltd; Basel Switzerland

Funder

University Hospital Basel

Publisher

Wiley

Subject

Pharmacology

Reference73 articles.

1. Serotonin Syndrome: analysis of cases registered in the French pharmacovigilance database;Abadie;J Clin Psychopharmacol,2015

2. The concise guide to PHARMACOLOGY 2017/18: Transporters;Alexander;Br J Pharmacol,2017a

3. The concise guide to PHARMACOLOGY 2017/18: G protein-coupled receptors;Alexander;Br J Pharmacol,2017b

4. Actions of tramadol, its enantiomers and principal metabolite, O-desmethyltramadol, on serotonin (5-HT) efflux and uptake in the rat dorsal raphe nucleus;Bamigbade;Br J Anaesth,1997

5. Effects of opioids on human serotonin transporters;Barann;Naunyn Schmiedebergs Arch Pharmacol,2015

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