Pharmacokinetics and pharmacodynamics of γ-hydroxybutyrate in healthy subjects

Author:

Liechti Matthias E.1,Quednow Boris B.2,Liakoni Evangelia1,Dornbierer Dario2,von Rotz Robin2,Gachet Maria Salomé3,Gertsch Jürg3,Seifritz Erich2,Bosch Oliver G.2

Affiliation:

1. Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research; University Hospital Basel; Βasel CH-4031 Switzerland

2. Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric Hospital; University of Zurich; Lenggstrasse 31 Zurich CH-8032 Switzerland

3. Institute of Biochemistry and Molecular Medicine; University of Bern; Bühlstrasse 28 Bern CH-3012 Switzerland

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference28 articles.

1. Evidence for a G protein-coupled γ-hydroxybutyric acid receptor;Snead;J Neurochem,2000

2. Regulation of γ-aminobutyric acid (GABA) release in cerebral cortex in the γ-hydroxybutyric acid (GHB) model of absence seizures in rat;Hu;Neuropharmacology,2000

3. From the street to the brain: neurobiology of the recreational drug γ-hydroxybutyric acid;Wong;Trends Pharmacol Sci,2004

4. Clinical course of γ-hydroxybutyrate overdose;Chin;Ann Emerg Med,1998

5. Gamma-hydroxybutyrate (GHB) and gamma-butyrolactone (GBL): analysis of overdose cases reported to the Swiss toxicological information centre;Liechti;Swiss Med Wkly,2004

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