In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization

Author:

Shaw C. D.1,Lonchamp J.1,Downing T.23,Imamura H.4,Freeman T. M.5,Cotton J. A.2,Sanders M.2,Blackburn G.67,Dujardin J. C.46,Rijal S.8,Khanal B.8,Illingworth C. J. R.5,Coombs G. H.1,Carter K. C.1

Affiliation:

1. Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde; 161 Cathedral Street Glasgow G4 0RE UK

2. Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus; Cambridge UK

3. College of Science, NUI Galway; Galway Ireland

4. Department of Biomedical Sciences; Instituut voor Tropische Geneeskunde Nationalestraat; Antwerpen Belgium

5. Department of Genetics; University of Cambridge; Cambridge UK

6. Department of Biomedical Sciences; University of Antwerp; Universiteitsplein 1 Antwerpen Belgium

7. Glasgow Polyomics, University of Glasgow; Glasgow

8. BP Koirala Institute of Health Sciences; Dharan Nepal

Funder

European Commission

Wellcome Trust Sanger Institute

BBSRC Research Experience Placement

Wellcome Trust and the Royal Society

National Science Foundation

Publisher

Wiley

Subject

Molecular Biology,Microbiology

Reference57 articles.

1. A method and server for predicting damaging missense mutations;Adzhubei;Nat Methods,2010

2. Leishmaniasis worldwide and global estimates of its incidence;Alvar;PLoS One,2012

3. Spread of artemisinin resistance in Plasmodium falciparum malaria;Ashley;N Engl J Med,2014

4. Metabolic adaptations of Leishmania donovani in relation to differentiation, drug resistance, and drug pressure;Berg;Mol Microbiol,2013

5. Experimental resistance to drug combinations in Leishmania donovani: Metabolic and phenotypic adaptations;Berg;Antimicrob Agents Chemother,2015

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3