Genome-wide exploration identifies sex-specific genetic effects of alleles upstream NPY to increase the risk of severe periodontitis in men

Author:

Freitag-Wolf Sandra1,Dommisch Henrik2,Graetz Christian3,Jockel-Schneider Yvonne4,Harks Inga5,Staufenbiel Ingmar6,Meyle Joerg7,Eickholz Peter8,Noack Barbara9,Bruckmann Corinna10,Gieger Christian11,Jepsen Søren2,Lieb Wolfgang12,Schreiber Stefan13,König Inke R.14,Schaefer Arne S.13

Affiliation:

1. Institute of Medical Informatics and Statistics; Christian-Albrechts-University Kiel; Kiel Germany

2. Department of Periodontology, Operative and Preventive Dentistry; Rheinische-Friedrichs-Wilhelm-University; Bonn Germany

3. Department of Operative Dentistry and Periodontology; Campus Kiel; University Medical Center Schleswig-Holstein; Kiel Germany

4. Department of Periodontology; Clinic of Preventive Dentistry and Periodontology; University Medical Center of the Julius-Maximilians-University; Würzburg Germany

5. Center of Periodontology, Operative and Preventive Dentistry; University Medical Center Münster; Münster Germany

6. Department of Conservative Dentistry, Periodontology and Preventive Dentistry; Hannover Medical School; Hannover Germany

7. Department of Periodontology; University Medical Center Giessen and Marburg; Giessen Germany

8. Department of Periodontology; Centre for Dental, Oral, and Maxillofacial Medicine (Carolinum); Johann Wolfgang Goethe-University; Frankfurt am Main Germany

9. University Medical Center Carl Gustav Carus der Technischen Universität Dresden; Center of Periodontology, Operative and Preventive Dentistry; Clinic of Preventive Dentistry; Dresden Germany

10. Department of Conservative Dentistry and Periodontology; Bernhard Gottlieb University Clinic of Dentistry; Vienna Austria

11. Institute of Genetic Epidemiology; Helmholtz Zentrum München; German Research Center for Environmental Health; Neuherberg Germany

12. Institute of Epidemiology and Biobank popgen; University Medical Center Schleswig-Holstein; Kiel Germany

13. Institute for Clinical Molecular Biology; Christian-Albrechts-University Kiel; Kiel Germany

14. Institute for Medical Biometry and Statistics; University of Lübeck; University Hospital Schleswig-Holstein; Lübeck Germany

Funder

Deutsche Forschungsgemeinschaft

Excellence Cluster “Inflammation at Interfaces”

German Research Foundation

German Ministry for Education and Research

Helmholtz Zentrum München - German Research Center for Environmental Health

German Federal Ministry of Education and Research

State of Bavaria

Publisher

Wiley

Subject

Periodontics

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