Analysis of a 5‐year, evidenced‐based, rational blood utilisation project in a South African regional hospital

Author:

Wise Robert123ORCID,Hood Kirsten4,Bishop David1ORCID,Sharp Gary5ORCID,Rodseth Reitze67ORCID,

Affiliation:

1. Discipline of Anaesthesiology and Critical Care, School of Clinical Medicine University of KwaZulu‐Natal Durban South Africa

2. Adult Intensive Care Unit, John Radcliffe Hospital Oxford University Hospitals NHS Foundation Trust Oxford UK

3. Faculty Medicine and Pharmacy Vrije Universiteit Brussel (VUB) Brussels Belgium

4. Department of Anaesthesia and Perioperative Medicine Groote Schuur Hospital and University of Cape Town Cape Town South Africa

5. Statistics Department Nelson Mandela University, South Campus Port Elizabeth South Africa

6. Department of Anaesthetics Nelson R Mandela School of Medicine, University of KwaZulu‐Natal Pietermaritzburg South Africa

7. Netcare Limited Sandton South Africa

Abstract

AbstractBackgroundBlood products are a lifesaving but limited resource, particularly in resource‐limited settings. Evidence‐based transfusion criteria tailored to local hospitals have shown great promise in reducing costs, minimising shortages, and ameliorating the morbidity and mortality associated with liberal blood product usage. We implemented the “Saving Blood, Saving Lives” project to: promote responsible blood product use and reduce blood product ordering inefficiencies and expenditure.MethodsA comprehensive change management programme, preceded by 3 months of clinical department consultation and training, was implemented. A new evidence‐based protocol for blood product utilisation was developed, together with an accountability form. This form was used in monthly audit meetings to refine policies, identify new problems, improve communication, and to drive hospital staff accountability and training. The primary measure of the programme's success was the change in the number of red cell concentrate units ordered.ResultsProject implementation required minimal time and no additional budget or staff. Annual red cell concentrate usage reduced from 7211 units in year one to 4077 units in year 5 (p < 0.001). Similar reductions were seen in freeze‐dried plasma and platelet usage, as well as administrative costs. Total project saving, adjusted to baseline admission numbers, amounted to over R46 million ($2.5 million).ConclusionsAs a change management programme centred the “Saving Blood, Saving Lives” project, was able to significantly reduce blood product‐related administration and expenditure by implementing evidence‐based transfusion criteria. The programme is simple, replicable and cost effective, making it ideally suited for use in resource‐constrained environments.

Publisher

Wiley

Subject

Hematology

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