Hypomethylating agent alters the immune microenvironment in acute myeloid leukaemia (AML) and enhances the immunogenicity of a dendritic cell/AML vaccine
Author:
Affiliation:
1. Beth Israel Deaconess Medical Center Harvard Medical School Boston MAUSA
2. The University of Texas MD Anderson Cancer Center Houston TX USA
3. Dana‐Farber Cancer Institute Department of Medical Oncology Boston MA
Funder
Astex Pharmaceuticals
WES (When Everyone Survives) Foundation
Dana-Farber Harvard Cancer Center (DFHCC) Leukemia Spore Career Enhancement Award
Publisher
Wiley
Subject
Hematology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.15818
Reference43 articles.
1. Regulation of cancer germline antigen gene expression: implications for cancer immunotherapy
2. The DNA demethylating agent 5-aza-2′-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells
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4. Immune checkpoint blockade in hematologic malignancies
5. Harnessing the immune system in acute myeloid leukaemia
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