Both gain‐of‐function and loss‐of‐functionde novoCACNA1Amutations cause severe developmental epileptic encephalopathies in the spectrum of Lennox‐Gastaut syndrome-Reference-Cited by-同舟云学术

Both gain‐of‐function and loss‐of‐functionde novoCACNA1Amutations cause severe developmental epileptic encephalopathies in the spectrum of Lennox‐Gastaut syndrome

Published:2019-08-29 Issue:9 Volume:60 Page:1881-1894
ISSN:0013-9580
Container-title:Epilepsia
language:en
Short-container-title:Epilepsia

Author:

Jiang Xiao¹²,Raju Praveen K.¹²,D'Avanzo Nazzareno³,Lachance Mathieu¹,Pepin Julie²,Dubeau François⁴,Mitchell Wendy G.⁵,Bello‐Espinosa Luis E.⁶,Pierson Tyler M.⁷,Minassian Berge A.⁸,Lacaille Jean‐Claude²^ORCID,Rossignol Elsa¹²^ORCID

Affiliation:

1. Sainte-Justine University Hospital Center, University of Montréal Montréal Canada

2. Department of Neurosciences University of Montréal Montreal Canada

3. Department of Pharmacology and Physiology University of Montréal Montréal Canada

4. Department of Neurosciences The Montreal Neurological Institute McGill University Montréal Canada

5. Neurology Division Children's Hospital Los Angeles & Department of Neurology Keck School of Medicine of University of Southern California Los Angeles CA USA

6. Department of Clinical Neurosciences University of Calgary Alberta Canada

7. Departments of Pediatrics and Neurology The Board of Governors Regenerative Medicine Institute Los Angeles CA USA

8. The Hospital for Sick Children Research Institute Toronto Canada

Funder

Canadian Institutes of Health Research

Fonds de Recherche du Québec - Santé

Savoy Foundation

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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