CCR5gene polymorphism affects the risk of GvHD after haematopoietic stem cell transplantation from an unrelated donor

Author:

Bogunia-Kubik Katarzyna1,Mizia Sylwia2,Gronkowska Anna3,Nowak Jacek4,Kyrcz-Krzemień Sławomira5,Markiewicz Mirosław5,Dzierżak-Mietła Monika5,Koclęga Anna5,Sędzimirska Mariola2,Suchnicki Krzysztof2,Duda Dorota2,Lange Janusz2,Mordak-Domagała Monika2,Kościńska Katarzyna2,Węzik Sławomir2,Jędrzejczak Wiesław W.3,Kaczmarek Beata3,Hellmann Andrzej6,Kucharska Agnieszka6,Kowalczyk Jerzy7,Drabko Katarzyna7,Warzocha Krzysztof4,Mika-Witkowska Renata4,Goździk Jolanta8,Lange Andrzej12,

Affiliation:

1. L. Hirszfeld Institute of Immunology and Experimental Therapy; Polish Academy of Sciences; Wroclaw Poland

2. Lower Silesian Centre for Cellular Transplantation with National Bone Marrow Donor Registry; Wroclaw Poland

3. Department of Haematology, Oncology and Internal Medicine; Medical University of Warsaw; Warsaw Poland

4. Institute of Haematology and Transfusion Medicine; Warsaw Poland

5. Department of Haematology and Bone Marrow Transplantation; Medical University of Silesia; Katowice Poland

6. Department of Hematology and Transplantology; Medical University of Gdansk; Gdansk Poland

7. Department of Paediatric Haematology, Oncology and Transplantology; Medical University; Lublin Poland

8. Chair of Clinical Immunology and Transplantation Polish-American Institute of Pediatrics; Jagiellonian University Medical College; Department of Transplantation Children's University Hospital; Cracow Poland

Funder

The National Centre for Research and Development

Publisher

Wiley

Subject

Hematology

Reference10 articles.

1. CCR5 deletion mutation and its association with the risk of developing acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation;Bogunia-Kubik;Haematologica,2006

2. The presence of functional CCR5 and EBV reactivation after allogeneic haematopoietic stem cell transplantation;Bogunia-Kubik;Bone Marrow Transplantation,2007

3. CCR5 expression on cells from HLA-matched unrelated marrow donors and graft-versus-host disease;Ma;Biology of Blood and Marrow Transplantation,2010

4. Donor and recipient chemokine receptor CCR5 genotype is associated with survival after bone marrow transplantation;McDermott;Blood,2010

5. Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction;Murai;Nature Immunology,2003

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