The pharmacokinetics of methadone and its metabolites in neonates, infants, and children

Author:

Ward Robert M.1,Drover David R.2,Hammer Gregory B.3,Stemland Christopher J.4,Kern Steve56,Tristani-Firouzi Martin7,Lugo Ralph A.8,Satterfield Kristin5,Anderson Brian J.9

Affiliation:

1. Department of Neonatology & Pediatric Clinical Pharmacology; University of Utah; Salt Lake City UT USA

2. Department of Anesthesia; Stanford University School of Medicine; Stanford CA USA

3. Department of Anesthesia and Pediatrics; Stanford University School of Medicine; Stanford CA USA

4. Department of Anesthesiology; University of Virginia; Charlottesville VA USA

5. Department of Pharmaceutics; University of Utah College of Pharmacy; Salt Lake City UT USA

6. Department of Anesthesiology; University of Utah; Salt Lake City UT USA

7. Divison of Pediatric Cardiology; University of Utah; Salt Lake City UT USA

8. Department of Pharmacotherapy; University of Utah College of Pharmacy; Salt Lake City UT USA

9. Department of Anaesthesiology; University of Auckland; Auckland New Zealand

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine,Pediatrics, Perinatology, and Child Health

Reference25 articles.

1. Perioperative pharmacokinetics of methadone in adolescents;Sharma;Anesthesiology,2011

2. Pharmacologic observations on the neonatal withdrawal syndrome;Rosen;J Pediatr,1976

3. Methadone levels and neonatal withdrawal;Mack;J Paediatr Child Health,1991

4. Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model;Yang;J Pharmacokinet Pharmacodyn,2006

5. The pharmacokinetics of methadone in adolescents undergoing posterior spinal fusion;Stemland;Pediatr Anesth,2013

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