A phase I/II study of oral clofarabine plus low-dose cytarabine in previously treated acute myeloid leukaemia and high-risk myelodysplastic syndrome patients at least 60 years of age
Author:
Affiliation:
1. Division of Clinical Research; Fred Hutchinson Cancer Research Center; Seattle WA USA
2. Department of Medicine; University of Washington; Seattle WA USA
3. Department of Laboratory Medicine; University of Washington; Seattle WA USA
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjh.13437/fullpdf
Reference14 articles.
1. Age and acute myeloid leukemia;Appelbaum;Blood,2006
2. Clofarabine doubles the response rate in older patients with acute myeloid leukemia but does not improve survival;Burnett;Blood,2013
3. Acute myeloid leukemia treatment in patients over 60 years of age. Comparison of symptomatic, palliative, and aggressive therapy;Doubek;Neoplasma,2005
4. Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias;Faderl;Blood,2005
5. A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome;Faderl;Blood,2008
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