Activated prothrombin complex concentrate (APCC)-mediated activation of factor (F)VIII in mixtures of FVIII and APCC enhances hemostatic effectiveness
Author:
Affiliation:
1. Department of Pediatrics; Nara Medical University; Kashihara Nara Japan
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jth.12197/fullpdf
Reference20 articles.
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2. The factor VIII complex: structure and function;Hoyer;Blood,1981
3. Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity;Eaton;Biochemistry,1986
4. Association of the factor VIII light chain with von Willebrand factor;Lollar;J Biol Chem,1988
5. Risk factors for inhibitor development in hemophilia A;Oldenburg;Haemotologica,2000
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