Rap1‐mediated nucleosome displacement can regulate gene expression in senescent cells without impacting the pace of senescence-Reference-Cited by-同舟云学术

Rap1‐mediated nucleosome displacement can regulate gene expression in senescent cells without impacting the pace of senescence

Published:2019-11-19 Issue:1 Volume:19 Page:
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Song Shufei¹²³^ORCID,Perez Javier V.³,Svitko William³,Ricketts M. Daniel¹⁴,Dean Elliot⁵,Schultz David⁵,Marmorstein Ronen¹⁴^ORCID,Johnson F. Brad¹³⁶^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biophysics University of Pennsylvania Philadelphia PA USA

2. Graduate Group in Biochemistry and Molecular Biophysics University of Pennsylvania Philadelphia PA USA

3. Department of Pathology and Laboratory Medicine University of Pennsylvania Philadelphia PA USA

4. Abramson Family Cancer Research Institute University of Pennsylvania Philadelphia PA USA

5. High‐Throughput Screening Core University of Pennsylvania Philadelphia PA USA

6. Institute on Aging University of Pennsylvania Philadelphia PA USA

Funder

American Heart Association

National Institute on Aging

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.13061

Reference80 articles.

1. Chromatin Disassembly Mediated by the Histone Chaperone Asf1 Is Essential for Transcriptional Activation of the Yeast PHO5 and PHO8 Genes

2. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

3. Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

4. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

5. Essential Role for the SANT Domain in the Functioning of Multiple Chromatin Remodeling Enzymes

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