Relapse in teenage and young adult patients treated on a paediatric minimal residual disease stratified ALL treatment protocol is associated with a poor outcome: results from UKALL2003-Reference-Cited by-同舟云学术

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Relapse in teenage and young adult patients treated on a paediatric minimal residual disease stratified ALL treatment protocol is associated with a poor outcome: results from UKALL2003

Published:2018-04-24 Issue:4 Volume:181 Page:515-522
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Sellar Rob S.¹²^ORCID,Rowntree Clare³,Vora Ajay J.⁴,Furness Caroline L.⁵^ORCID,Goulden Nicholas⁶,Mitchell Chris⁷,Moorman Anthony V.⁸,Hough Rachael¹²^ORCID

Affiliation:

1. Cancer Institute; University College London; London United Kingdom

2. Department of Haematology; University College London Hospitals; London United Kingdom

3. University Hospital of Wales; Cardiff United Kingdom

4. Department of Paediatric Haematology; The Children's Hospital; Sheffield United Kingdom

5. Haemato-Oncology; Royal Marsden NHS Foundation Trust; London United Kingdom

6. Department of Haematology; Great Ormond Street Hospital for Children; London United Kingdom

7. John Radcliffe Hospital; Oxford United Kingdom

8. Northern Institute for Cancer Research; Newcastle University; Newcastle upon Tyne United Kingdom

Funder

Bloodwise

Medical Research Council

National Institute for Health Research

Biomedical Research Centres

Publisher

Wiley

Subject

Hematology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjh.15208/fullpdf

Reference19 articles.

1. Should adolescents with acute lymphoblastic leukemia be treated as old children or young adults? Comparison of the French FRALLE-93 and LALA-94 trials;Boissel;Journal of Clinical Oncology,2003

2. Significant difference in outcome for adolescents with acute lymphoblastic leukemia treated on pediatric vs adult protocols in the Netherlands;Bont;Leukemia,2004

3. Acute lymphoblastic leukemia relapsing after first-line pediatric-inspired therapy: a retrospective GRAALL study;Desjonqueres;Blood Cancer Journal,2016

4. Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study;Fielding;Blood,2007

5. Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation;Gokbuget;Blood,2012

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1. Unusual relapse of low hypodiploid acute lymphoblastic leukaemia in a family with Li‐Fraumeni syndrome;Pediatric Blood & Cancer;2023-05-28

2. Multiple CAR-T cell therapy for acute B-cell lymphoblastic leukemia after hematopoietic stem cell transplantation: A case report;Frontiers in Immunology;2022-11-17

3. Multicenter comparison of first salvage chemotherapy versus novel therapy regimens in adult relapsed/refractory acute lymphoblastic leukemia;Leukemia & Lymphoma;2022-03-28

4. An MRD-stratified pediatric protocol is as deliverable in adolescents and young adults as in children with ALL;Blood Advances;2021-12-20

5. T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes;Nature Biotechnology;2021-12-06

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