Fixed airflow obstruction relates to eosinophil activation in asthmatics

Author:

Mogensen Ida12ORCID,Alving Kjell3,Dahlen Sven-Erik4,James Anna4,Forsberg Bertil5,Ono Junya6,Ohta Shoichiro7,Venge Per8,Borres Magnus P.3,Izuhara Kenji9,Janson Christer1ORCID,Malinovschi Andrei2

Affiliation:

1. Department of Medical Sciences; Lung Allergy and Sleep research; Uppsala University; Uppsala Sweden

2. Department of Medical Sciences; Clinical Physiology; Uppsala University; Uppsala Sweden

3. Department of Women's and Children's Health; Uppsala University; Uppsala Sweden

4. Experimental Asthma and Allergy Research; National Institute of Environmental Medicine; Karolinska Institutet; Stockholm Sweden

5. Department of Public Health and Clinical Medicine; Occupational and Environmental Medicine; Umeå University; Umeå Sweden

6. Shino-Test Corporation Ltd.; Sagamihara Japan

7. Department of Laboratory Medicine; Saga Medical School; Saga Japan

8. Department of Medical Sciences; Clinical Chemistry; Uppsala University; Uppsala Sweden

9. Division of Medical Biochemistry; Department of Biomolecular Sciences; Saga Medical School; Saga Japan

Funder

EU FP6 project GA(2)LEN

Karolinska Institutet

Vetenskapsrådet

Vårdalstiftelsen

Stockholms Läns Landsting

Astma- och Allergiförbundet

Stiftelsen för Strategisk Forskning

Konsul Th C Berghs Foundation

Karolinska Institutet SciLifeLab Collaborations on Translational Medicine (ChAMP) project

U4 network

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference46 articles.

1. Global Initiative for Asthma 2017 http://ginasthma.org/2017-gina-report-global-strategy-for-asthma-management-and-prevention/

2. Asthma therapy and airway remodeling;Mauad;J Allergy Clin Immunol,2007

3. Early thickening of the reticular basement membrane in children with difficult asthma;Payne;Am J Respir Crit Care Med,2003

4. Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers;Saglani;Am J Respir Crit Care Med,2007

5. Long-term effects of budesonide or nedocromil in children with asthma;Szefler;N Engl J Med,2000

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