Novel soluble guanylyl cyclase activators increase glomerular cGMP, induce vasodilation and improve blood flow in the murine kidney

Author:

Stehle Daniel1ORCID,Xu Min Ze2,Schomber Tibor3,Hahn Michael G.3,Schweda Frank4,Feil Susanne1,Kraehling Jan R.3,Eitner Frank35,Patzak Andreas2,Sandner Peter36ORCID,Feil Robert1ORCID,Bénardeau Agnès37

Affiliation:

1. Interfakultäres Institut für Biochemie (IFIB) University of Tübingen Tübingen Germany

2. Institute of Vegetative Physiology Charité‐Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt‐Universität zu Berlin Berlin Germany

3. Bayer AG, Cardiovascular Research Pharma Research Center Wuppertal Germany

4. Institut für Physiologie Universität Regensburg Regensburg Germany

5. Division of Nephrology and Clinical Immunology RWTH Aachen University Aachen Germany

6. Institute of Pharmacology Hannover Medical School Hannover Germany

7. Novo Nordisk A/S Cardio‐Renal Biology Måløv Denmark

Publisher

Wiley

Subject

Pharmacology

Reference54 articles.

1. The Concise Guide to PHARMACOLOGY 2019/20: Catalytic receptors;Alexander S. P. H.;British Journal of Pharmacology,2019

2. The novel soluble guanylyl cyclase (sGC) activator runcaciguat induced renal vasodilation and attenuated kidney damage in a rat CKD model;Benardeau A.;Journal of the American Society of Nephrology,2020

3. A Soluble Guanylate Cyclase Activator Inhibits the Progression of Diabetic Nephropathy in the ZSF1 Rat

4. Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy

5. Developing Treatments for Chronic Kidney Disease in the 21st Century

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