Tissue transglutaminase-catalysed cross-linking induces Apolipoprotein E multimers inhibiting Apolipoprotein E's protective effects towards amyloid-beta-induced toxicity

Author:

de Jager Mieke1,Drukarch Benjamin1,Hofstee Marloes1,Brevé John1,Jongenelen Cornelis A. M.1,Bol John G. J. M.1,Wilhelmus Micha M. M.1

Affiliation:

1. Department of Anatomy and Neurosciences; Neuroscience Campus Amsterdam; VU University Medical Center; Amsterdam The Netherlands

Funder

The Brain Foundation of the Netherlands

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference67 articles.

1. Localization of transglutaminase in hippocampal neurons: implications for Alzheimer's disease;Appelt;J. Histochem. Cytochem.,1996

2. Sporadic cerebral amyloid angiopathy: pathology, clinical implications, and possible pathomechanisms;Attems;Acta Neuropathol.,2005

3. Review: sporadic cerebral amyloid angiopathy;Attems;Neuropathol. Appl. Neurobiol.,2011

4. Lipoprotein (a) is a substrate for factor XIIIa and tissue transglutaminase;Borth;J. Biol. Chem.,1991

5. Apolipoprotein E protects cultured pericytes and astrocytes from D-Abeta(1-40)-mediated cell death;Bruinsma;Brain Res.,2010

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