Physiologically based pharmacokinetic modelling of the three-step metabolism of pyrimidine using 13C-uracil as an in vivo probe-Reference-Cited by-同舟云学术

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Physiologically based pharmacokinetic modelling of the three-step metabolism of pyrimidine using 13C-uracil as an in vivo probe

Published:2005-08-01 Issue:6 Volume:60 Page:584-593
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:

Author:

Ito Suminobu,Kawamura Takeshi,Inada Makoto,Inoue Yoshiharu,Hirao Yukihiro,Koga Toshihisa,Kunizaki Jun-ichi,Shimizu Takefumi,Sato Hitoshi

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.2005.02472.x/fullpdf

Reference43 articles.

1. Metabolic fate of pyrimidines and purines in dietary nucleic acids ingested by mice;Sonoda;Biochim Biophys Acta,1978

2. Pyrimidine catabolism: individual characterization of the three sequential enzymes with a new assay;Traut;Biochemistry,1984

3. Pyrimidine metabolism. Enzymatic pathway of uracil and thymine degradation;Canellakis;J Biol Chem,1956

4. Catabolism of C14-labelled uracil, dihydrouracil and β-ureidopropionic acid in rat liver slices;Fritzson;J Biol Chem,1957

5. Clinical pharmacology of 5-fluorouracil;Diasio;Clin Pharmacokinet,1989

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