Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction
Author:
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.2009.03572.x/fullpdf
Reference23 articles.
1. Comparison of the antitussive effects of codeine phosphate 20 mg, dextromethorphan 30 mg and noscapine 30 mg using citric acid-induced cough in normal subjects;Empey;Eur J Clin Pharmacol,1979
2. Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells;Ye;Proc Natl Acad Sci USA,1998
3. Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth;Landen;Clin Cancer Res,2004
4. p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells;Aneja;Cancer Res,2007
5. Preclinical pharmacokinetics and bioavailability of noscapine, a tubulin-binding anticancer agent;Aneja;Cancer Chemoth Pharm,2007
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