Immediate haemodynamic effects of a novel partial agonist, beta 1- adrenoceptor blocking drug ICI 141,292 after intravenous administration to healthy young volunteers and patients with ischaemic heart disease.

Author:

Bonde J,Svendsen TL,Lyngborg K,Mehlsen J,Trap-Jensen J

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference15 articles.

1. Akhras , F. Smyth , P. Jeffries , S. Jackson , G. 1985 Visacor, a new once daily cardioselective beta-blocker with intrinsic sympathomimetic activity for stable angina Cardiovascular Pharmacotherapy International Symposium

2. Thermodilution cardiac output determination with a single flow directed catheter;Forrester;Am. Heart J.,1972

3. The demonstration of ICI 141292 as a β-adrenoceptor blocking agent in man;Harry;Br. J. clin. Pharmac.,1984

4. Influence of intrinsic sympathomimetic activity of β-adrenoceptor blockers on the heart rate and blood pressure responses to gradual exercise;Jennings;Br. J. clin. Pharmac.,1981

5. Does beta-1 selective agonistic activity interfere with antihypertensive efficacy of beta-1 selective blocking agents;Leonetti;Ricerca Scientifica ed Educazione Permanente,1985

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