Pralatrexate, a novel class of antifol with high affinity for the reduced folate carrier-type 1, produces marked complete and durable remissions in a diversity of chemotherapy refractory cases of T-cell lymphoma

Author:

O'Connor Owen A.,Hamlin Paul A.,Portlock Carol,Moskowitz Craig H.,Noy Ariela,Straus David J.,MacGregor-Cortelli Barbara,Neylon Ellen,Sarasohn Debra,Dumetrescu Otila,Mould Diane R.,Fleischer Martin,Zelenetz Andrew D.,Sirotnak Frank,Horwitz Steven

Publisher

Wiley

Subject

Hematology

Reference12 articles.

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2. Prognostic significance of T-cell phenotype in aggressive non-Hodgkin's lymphomas. Groupe d'Etudes des Lymphomes de l'Adulte (GELA);Gisselbrecht;Blood,1998

3. Phase I and pharmacokinetic study of 10-propargyl-10-deazaaminopterin, a new antifolate;Krug;Clinical Cancer Research,2000

4. 10-propargyl-10-deazaaminopterin: an antifolate with activity in patients with previously treated non-small cell lung cancer;Krug;Clinical Cancer Ressearch,2003

5. Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001;Morton;Blood,2005

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