The fraction of recombinant factor VIII:Ag unable to bind von Willebrand factor has no FVIII coagulant activity: studiesin vitro

Author:

Ofosu F. A.1,Tse H.1,Naqvi A.1,Bhakta H.1,Song Y.1

Affiliation:

1. Department of Pathology and Molecular Medicine; McMaster University; Hamilton; ON; Canada

Publisher

Wiley

Subject

Genetics (clinical),Hematology,General Medicine

Reference32 articles.

1. First and second-generation recombinant factor VIII concentrates in previously untreated patients recovery, safety, efficacy, and inhibitor development;Lusher;Semin Thromb Hemost,2002

2. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia A;Manco-Johnson;New England J Med,2007

3. Influence of the type of factor VIII concentrate on the incidence of factor VIII inhibitors in previously untreated patients with severe hemophilia A;Goudemand;Blood,2006

4. Epidemiology of inhibitors and current treatment strategies;Kreuz;Haematologica,2003

5. The epidemiology of inhibitors in hemophilia A: a systematic review;Wright;Haemophilia,2003

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