Dosing and effectiveness of recombinant activated factor VII (rFVIIA) in congenital haemophilia with inhibitors by bleed type and location: the experience of the Haemophilia and Thrombosis Research Society (HTRS) Registry (2004-2008)
Author:
Affiliation:
1. Children's Center for Cancer and Blood Disorders; Children's Hospital Los Angeles; University of Southern California Keck School of Medicine; Los Angeles; CA
2. Novo Nordisk Inc.; Princeton; NJ; USA
Publisher
Wiley
Subject
Genetics (clinical),Hematology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2516.2012.02864.x/fullpdf
Reference15 articles.
1. Mechanism of action of factor VIIa in the treatment of coagulopathies;Hedner;Semin Thromb Hemost,2006
2. Clinical experience with recombinant factor VIIa;Lusher;Blood Coagul Fibrinolysis,1998
3. A randomized, double-blind comparison of two dosage levels of recombinant factor VIIa in the treatment of joint, muscle and mucocutaneous haemorrhages in persons with haemophilia A and B, with and without inhibitors. rFVIIa Study Group;Lusher;Haemophilia,1998
4. Home treatment of mild to moderate bleeding episodes using recombinant factor VIIa (Novoseven) in haemophiliacs with inhibitors;Key;Thromb Haemost,1998
5. Single 270 microg kg(-1)-dose rFVIIa vs. standard 90 microg kg(-1)-dose rFVIIa and APCC for home treatment of joint bleeds in haemophilia patients with inhibitors: a randomized comparison;Young;Haemophilia,2008
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1. Current status and future prospects of activated recombinant coagulation factor VIIa, NovoSeven®, in the treatment of haemophilia and rare bleeding disorders;Annals of Hematology;2023-06-30
2. Factor VIIa treatment increases circulating extracellular vesicles in hemophilia patients: Implications for the therapeutic hemostatic effect of FVIIa;Journal of Thrombosis and Haemostasis;2022-08
3. Transfusion Therapy in Specific Clinical Situations;Transfusion Medicine;2021-03-02
4. The evolution of factor VIIa in the treatment of bleeding in haemophilia with inhibitors;Haemophilia;2019-09-05
5. A case of severe hemophilia A with inhibitor suffered from difficult hemostatic management after tooth extraction;Japanese Journal of Oral and Maxillofacial Surgery;2019-08-20
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