Antibody formation and specificity in Bethesda-negative brother pairs with haemophilia A
Author:
Affiliation:
1. Centre for Thrombosis and Haemostasis; Skåne University Hospital; Lund University; Malmö; Sweden
2. Department of Biostatistics Rho Inc; Chapel Hill; NC; USA
Publisher
Wiley
Subject
Genetics (clinical),Hematology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2516.2012.02903.x/fullpdf
Reference26 articles.
1. High incidence of anti-FVIII antibodies against non-coagulant epitopes in haemophilia A patients: a possible role for the half-life of transfused FVIII;Dazzi;Br J Haematol,1996
2. Anti-factor VIII antibodies of hemophiliac patients are frequently directed towards nonfunctional determinants and do not exhibit isotypic restriction;Gilles;Blood,1993
3. Low detection rate of antibodies to non-functional epitopes on factor VIII in patients with hemophilia A and negative for inhibitors by Bethesda assay;Ling;J Thromb Haemost,2003
4. Low factor VIII recovery in haemophilia A patients without inhibitor titre is not due to the presence of anti-factor VIII antibodies undetectable by the Bethesda assay;Mondorf;Haemophilia,2001
5. Noncoagulation inhibitory factor VIII antibodies after induction of tolerance to factor VIII in hemophilia A patients;Nilsson;Blood,1990
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