Pharmacokinetic/pharmacodynamic models for the depletion of Vbeta5.2/5.3 T cells by the monoclonal antibody ATM-027 in patients with multiple sclerosis, as measured by FACS-Reference-Cited by-同舟云学术

Pharmacokinetic/pharmacodynamic models for the depletion of Vbeta5.2/5.3 T cells by the monoclonal antibody ATM-027 in patients with multiple sclerosis, as measured by FACS

Published:2004-10 Issue:4 Volume:58 Page:378-389
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Zingmark Per-Henrik,Edenius Charlotte,Karlsson Mats O.

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2125.2004.02177.x/fullpdf

Reference16 articles.

1. Autoimmunity to Collagen II and Myelin Basic Protein: Comparative Studies in Humans and Rodents

2. Depletion of V5.2/5.3 T cells with a humanized antibody in patients with multiple sclerosis

3. Antibody-mediated suppression of Vβ5.2/5.3+T cells in multiple sclerosis: Results from an MRI-monitored phase II clinical trial

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