A novel dysfunctional protein C (Protein C Padua 2) associated with a thrombotic tendency: substitution of Cys for Arg-1 results in a strongly reduced affinity for binding of Ca++-Reference-Cited by-同舟云学术

A novel dysfunctional protein C (Protein C Padua 2) associated with a thrombotic tendency: substitution of Cys for Arg-1 results in a strongly reduced affinity for binding of Ca++

Published:2008-03-12 Issue:3 Volume:85 Page:521-527
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:

Author:

Girolami A.,Simioni P.,Girolami B.,Marchiori A.,Millar D. S.,Bignell P.,Kakkar V. V.,Cooper D. N.

Publisher

Wiley

Subject

Hematology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1365-2141.1993.tb03342.x/fullpdf

Reference37 articles.

1. The use of a functional and immunologic assay for plasma protein C in the study of the heterogeneity of congenital protein C deficiency;Bertina;Thrombosis and Haemostasis,1984

2. Protein C deficiency in a Dutch family with thrombotic disease;Bertina;Thrombosis and Haemostasis,1982

3. Factor IX Zutphen. A genetic variant of blood coagulation factor IX with an abnormally high molecular weight;Bertina;Journal of Laboratory and Clinical Medicine,1982

4. Protein C Vermont: symptomatic type II protein C deficiency associated with two Gla domain mutations;Bovill;Blood,1992

5. Congenital Protein C deficiency and venous thromboembolism. A study of three Dutch families;Broekmans;New England Journal of Medicine,1983

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